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Glucose is used to make ATP in a cell. There are three major steps.

First glucose is broken down into two 3-carbon pyruvates in glycolysis. Two ATP are used to start this chain of reactions. The reaction produces 4 ATP (with a net of 2 ATP). It also produces 4 NADH from 4 NAD+. This step took place outside the mitochondrion. For the next phase it will move inside.

Next, in aerobic respiration (this is probably what your mean), each of the 2 pyruvates will go through the Citric Acid/Krebs cycle. So multiply the products for one pyruvate by two to get the products for the full glucose. Here the pyruvates are first converted to Acetal CoA to prepare for the cycle, producing 1 NADH and 1 CO2. After completing the cycle (ending with oxaloacetate), the pyruvate will have produced 3 more NADH, 1 FADH2 from FAD+, and 1 ATP. So far, the total products are 4 ATP, 10 NADH, and 2 FADH.

Now these enter the electron transport chain. In the ETC, one FADH2 to FAD+ will result in roughly 2 ATP and one NADH to NAD+ will result in 3. Because of how this phase is set up, these are only averages. The real number of ATP depends on the efficiency of the mitochondrion.

The 10 NADH from the previous steps will produce 30 ATP and the 2 FADH2 will produce 4. Add this with the other 4 ATP and you will end up with 38 ATP. This is the maximum amount. You will often see 38-36 ATP because of complications between glycolysis and the citric acid cycle. Most mitochondria will produce somewhere around 30 ATP because not all mitochondria are special.

If it is anaerobic then the process basically stops after glycolysis. The cell tries to free up some of the NADH so more glycolysis can occur.

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14y ago

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