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Amphetamines are psychostimulant
drugs of abuse and include methamphetamine, amphetamine and ecstacy
or MDMA. Amphetamine drugs can effect norepinephine in several ways. Initially amphetamine drugs will cause a massive release of all monoamine neurotransmitters (dopamine, serotonin and norepinephrine) from the vesicles inside the presynaptic
cleft of a neuron. Furthermore, amphetamine and methamphetamine (not MDMA) are very structurally similar to norepinephrine and can substitute, or move through, the norepinephrine transporter (NET) which regulates the amount of norepinephrine in the synapse. This can lead to dysregulation
of the transporter so that it no longer functions properly. This can happen in several ways including internalization of the transporter inside the presynaptic
cleft and/or phosphorylation of the transporter, which can essentially shut it off. This means that there is more norepinephrine in the synapse, which can bind to norepinephrine receptors and lead to the subjective (feeling), physiological, behavioral and neurobiological effects of amphetamine drugs.
What else can I help you with?
What chemicals do amphetamines cause your brain to release?
Amphetamine is 1-phenylpropan-2-amine. Amphetamines are drugs that increase levels of the neurotransmitters norepinephrine, serotonin, and dopamine in the brain. They are commonly used as stimulants and appetite suppressants.
Does norepinephrine cause a decrease in stroke volume?
Norepinephrine primarily acts as a vasoconstrictor and can increase heart contractility, which typically leads to an increase in cardiac output. However, in certain situations, such as when there is excessive vasoconstriction or under conditions of high vascular resistance, it may indirectly contribute to a decrease in stroke volume by reducing venous return. Overall, the effect of norepinephrine on stroke volume can vary depending on the physiological context.
Which is a mechanism for norepinephrine destruction?
Norepinephrine is primarily broken down by the enzyme monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT) in the liver and other tissues. MAO oxidizes norepinephrine into its metabolite, dihydroxyphenylglycol (DHPG), while COMT methylates norepinephrine into normetanephrine.
What are norepinephrine releasing fibers called?
Andrenergic fibers release Norepinephrine and Cholinergic fibers release Acetylcholine.
What is the final step in the release of norepinephrine from the sympathetic neuron?
The final step in the release of norepinephrine from the sympathetic neuron involves the fusion of vesicles containing norepinephrine with the cell membrane, leading to the release of norepinephrine into the synaptic cleft. This process is triggered by an action potential reaching the nerve terminal.
Amphetamines have stimulating effects on the nervous system because they?
release norepinephrine
What are the differences between amphetamines and methylphenidate in terms of their effects and mechanisms of action?
Amphetamines and methylphenidate are both stimulant medications used to treat conditions like ADHD. Amphetamines work by increasing the release of neurotransmitters like dopamine and norepinephrine, while methylphenidate works by blocking their reuptake. Amphetamines tend to have a more potent and immediate effect, while methylphenidate is considered to have a more gradual and sustained effect. Additionally, amphetamines have a higher potential for abuse and dependence compared to methylphenidate.
Amphetamines appear to exert their main effects by altering the release and reuptake of?
dopamine and norepinephrine
Amphetamines increase the release of what four chemicals in your body?
I only know of seratonin, dopamine, and norepinephrine (sp)
How do amphetamines work inside of the brain?
When amphetamines are activated they release something called norepinephrine. It also speeds up the heart and the metabolic process. The metabolic process transforms food to things the body can use.
What chemicals do amphetamines cause your brain to release?
Amphetamine is 1-phenylpropan-2-amine. Amphetamines are drugs that increase levels of the neurotransmitters norepinephrine, serotonin, and dopamine in the brain. They are commonly used as stimulants and appetite suppressants.
Can amphetamines be in cymbalta?
No, amphetamines are not an ingredient in Cymbalta (duloxetine). Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) primarily used to treat depression and anxiety disorders. Amphetamines are a different class of medications often used to treat ADHD and certain sleep disorders. Always consult a healthcare provider for specific medication information and interactions.
Do any cholesterol lowering drugs contain amphetamines?
No, there is no FDA approved drug for "cholesterol lowering" that contains amphetamines. It has no effect on cholesterol.
What has the author Scott E Lukas written?
Scott E. Lukas has written: 'Amphetamines' -- subject(s): Amphetamine, Amphetamine abuse, Amphetamines, Drug abuse, Drugs, Juvenile literature, Physiological effect, Toxicology 'Amphetamines (Encyclopedia of Psychoactive Drugs)' 'Amphetamines Danger in Fa'
What are the effect of ampethamine on your brain?
Amphetamines can effect the brain in many ways. The one time use effects may not be permanent, but chronic use effects can be very dangerous and permanent. If one was to use this drug on a long term, they could develop acne, dry and/or itchy skin, and psychotic episodes.
What drugs mimic norepinphrine?
Drugs that mimic norepinephrine, also known as noradrenaline, include sympathomimetic agents such as epinephrine, dopamine, and certain selective norepinephrine reuptake inhibitors (SNRIs) like venlafaxine and desvenlafaxine. These substances can stimulate adrenergic receptors, leading to effects such as increased heart rate and enhanced blood pressure. Other examples include amphetamines, which increase norepinephrine release in the brain, and certain nasal decongestants like phenylephrine.
How amphetamines and cocaine both cause feelings of pleasure?
Amphetamines and cocaine stimulate the release of dopamine, a neurotransmitter associated with pleasure and reward, in the brain. This increased dopamine activity leads to feelings of euphoria and pleasure. Additionally, both drugs can also increase levels of other neurotransmitters like norepinephrine and serotonin, contributing to their pleasurable effects.
