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Amphetamines are psychostimulant

drugs of abuse and include methamphetamine, amphetamine and ecstacy

or MDMA. Amphetamine drugs can effect norepinephine in several ways. Initially amphetamine drugs will cause a massive release of all monoamine neurotransmitters (dopamine, serotonin and norepinephrine) from the vesicles inside the presynaptic

cleft of a neuron. Furthermore, amphetamine and methamphetamine (not MDMA) are very structurally similar to norepinephrine and can substitute, or move through, the norepinephrine transporter (NET) which regulates the amount of norepinephrine in the synapse. This can lead to dysregulation

of the transporter so that it no longer functions properly. This can happen in several ways including internalization of the transporter inside the presynaptic

cleft and/or phosphorylation of the transporter, which can essentially shut it off. This means that there is more norepinephrine in the synapse, which can bind to norepinephrine receptors and lead to the subjective (feeling), physiological, behavioral and neurobiological effects of amphetamine drugs.

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Amphetamines have stimulating effects on the nervous system because they?

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No, there is no FDA approved drug for "cholesterol lowering" that contains amphetamines. It has no effect on cholesterol.


What has the author Scott E Lukas written?

Scott E. Lukas has written: 'Amphetamines' -- subject(s): Amphetamine, Amphetamine abuse, Amphetamines, Drug abuse, Drugs, Juvenile literature, Physiological effect, Toxicology 'Amphetamines (Encyclopedia of Psychoactive Drugs)' 'Amphetamines Danger in Fa'


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