OAA (oxaloacetate) is important in the Krebs' cycle because it combines with acetyl-CoA to form citrate, which is the starting compound in the cycle. Without OAA, the Krebs' cycle cannot proceed because there would be no citrate to kickstart the series of reactions that generate energy in the form of ATP.
Assuming that the Kreb cycle starts with the citrate, the third compound is alpha-ketoglutarate.
citrate
Citrate is formed through the citric acid cycle, also known as the Krebs cycle, which occurs in the mitochondria of cells. In this cycle, citrate is produced from the condensation of oxaloacetate and acetyl-CoA. It is an intermediate in the cycle that eventually leads to the production of ATP, the cell's main source of energy.
Acetyl CoA (acetyl group) is the compound that enters the Kreb Cycle.
Citrate
Since Krebs is a cycle, there is a pretty good argument that there is no "first metabolite". However, because citrate is a condensation product of OAA and acetyl-CoA, and acetyl-CoA is typically what is feeding in to the Krebs cycle, citrate could be considered the "first metabolite"
Pyruvate -> Acetyl CoA -> Citrate which is used by the Krebs or Citric Acid Cycle.
The starting molecule for the Krebs cycle is acetyl-CoA, which enters the cycle by combining with oxaloacetate to form citrate.
The Krebs cycle starts with acetyl CoA, and combines with oxaloacetate to form citrate, a six-carbon molecule. Citrate is further oxidized until oxaloacetate is again reached at the end to restart the Krebs cycle.
OAA (oxaloacetate) is important in the Krebs' cycle because it combines with acetyl-CoA to form citrate, which is the starting compound in the cycle. Without OAA, the Krebs' cycle cannot proceed because there would be no citrate to kickstart the series of reactions that generate energy in the form of ATP.
Assuming that the Kreb cycle starts with the citrate, the third compound is alpha-ketoglutarate.
citrate
List of enzymes used in Krebs cycle are: 1. citrate. 2. isocitrate. 3.alpha- ketoglutarate. 4. succinyl- CoA. 5. succinate. 6. fumarate. 7.malate. 8.oxaloacetate. Hope this helps.
The first six-carbon molecule produced in the Krebs cycle is citrate, also known as citric acid. It is formed by condensation of acetyl-CoA and oxaloacetate catalyzed by the enzyme citrate synthase.
The conguate base of citric acid - citrate - is an important intermediate in the cycle. This is where the name "Citric Acid Cycle" comes from. It is also known as the Tricarboxylic Acid Cycle - as it involves 3 carbon acids, or the Krebs Cycle after Hans Adolf Krebs - who developed the complexities of the cycle.
Citrate is formed through the citric acid cycle, also known as the Krebs cycle, which occurs in the mitochondria of cells. In this cycle, citrate is produced from the condensation of oxaloacetate and acetyl-CoA. It is an intermediate in the cycle that eventually leads to the production of ATP, the cell's main source of energy.