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Certain functional groups on the chemical structure of drugs are capable of being protonated/ deprotonated based on the pH of the solution (amine groups as well as carboxylate groups are capable of this). Changing the pH of the solution can change the physical chemistry of a drug by adding or removing protons at certain sites of the molecule. Depending on the molecule, this will either increase or decrease the solubility of the drug.
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Why many drugs are weak acids and weak bases?
This is necessary because drugs need to be able to pass through cell membranes ( that's exclude strong acids and bases) and dissolve in the stomach and blood ( that's favor acids and bases). If a compound is too basic or acidic, it won't be able to cross the cell membranes and leave the digestive tract; if it's not acidic or basic at all, it won't dissolve well in the blood so it won't be carried efficiently throughout the body. If you want to get a little more into the chemistry of it, acids and bases gain and lose protons, which gives them ionic charges. Charged particles dissolve well in water, so acids and bases dissolve well. Charged particles can't pass throu...gh layers of uncharged molecules like those that make up the cell membrane, though. Weak acids and bases have the advantage that they're sometimes in their ionized state and sometimes in their unionized state, so they can dissolve, get through the cell membrane and then re-dissolve in the blood.
Is Copper Nitrate Acidic or Basic?
It is acidic. it is formed by the reaction of Copper(2) Hydroxide which is a Weak base and Sulfuric Acid which is a strong Acid. A weak base + strong acid always gives an acidic salt.
Is hydrogen sulfide gas soluble in water?
Yes, hydrogen sulfide gas is soluble in water. It reacts with water to form hydrosulfuric acid, which is a weak acid. The solubility of hydrogen sulfide in water increases with decreasing temperature.
Is NH4 a weak acid?
Ammonium hydroxide (NH4OH) is a base. The cation (NH4)+ is low acidic.
Will a Strong acid and weak base will produce a neutral salt?
No, a strong acid and a weak base will not produce a neutral salt. Instead, the resulting salt will be acidic because the anion from the weak base does not fully neutralize the strong acid. This typically leads to a solution that is acidic when the salt is dissolved in water.
Is handwash a strong acid?
no. it is a weak acidic
Is NH4Br basic or acidic?
NH4Br is a salt that is formed from a weak base (NH4OH) and a strong acid (HBr). Since NH4Br is derived from a weak base, it exhibits acidic properties.
Is vinegar acidic or neutral?
Acidic. Vinegar contains the weak organic acid acetic acid.
What is the effect of a common ion on dissolution rate?
A common ion will reduce the solubility of an electrolyte with an identical ion. The common ion will hence also reduce the dissolution rate of the electrolyte. For example, the solubility of a HCl salt of a weak organic base may be reduced in a HCl solution.
Why many drugs are weak acids and weak bases?
This is necessary because drugs need to be able to pass through cell membranes ( that's exclude strong acids and bases) and dissolve in the stomach and blood ( that's favor acids and bases). If a compound is too basic or acidic, it won't be able to cross the cell membranes and leave the digestive tract; if it's not acidic or basic at all, it won't dissolve well in the blood so it won't be carried efficiently throughout the body. If you want to get a little more into the chemistry of it, acids and bases gain and lose protons, which gives them ionic charges. Charged particles dissolve well in water, so acids and bases dissolve well. Charged particles can't pass throu...gh layers of uncharged molecules like those that make up the cell membrane, though. Weak acids and bases have the advantage that they're sometimes in their ionized state and sometimes in their unionized state, so they can dissolve, get through the cell membrane and then re-dissolve in the blood.
What is the effect of weak governments?
an effect of the week governments is that they were really weak
Is bicarb acidic or basic?
Bicarbonate (bicarb) is a weak base.
Why are some salts still acidic or basic?
Salts can be acidic or basic depending on the cation and anion they are composed of. If the cation comes from a weak base or the anion comes from a weak acid, the salt can be acidic or basic. For example, ammonium chloride is acidic because the ammonium ion comes from a weak base (ammonia) while the chloride ion comes from a strong acid (hydrochloric acid).
What is the ratio of basic to acidic species for a weak acid with a pKa of 7.2 when the pH is 6.0?
The ratio of basic to acidic species for a weak acid with a pKa of 7.2 at a pH of 6.0 is 10:1.
How can solubility increase?
1) Strong solute-solvent greater solubility while weak solute-solvent attractions equate to lesser solubility 2) Temperature (for gaz high temperature decrease solubility) 3) Pressure for solubility gaz in liquid 4) Polarity of solvent: Like dissolves like
Is grape juice an acid or base?
It is an acid, a weak acid.
Is grape juice a strong or weak acid?
Grape juice is mildly acidic. It contains tartaric acid, a weak acid.
