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LC is liquid chromatograph, this uses a liquid mobile phase (reverse phase more common, employing a polar column such as water and MeOH/ACN) to elute analytes from a mixture through interaction with a stationary phase (non polar, C18 in reverse most common). Separation is based on polarity of the analytes.

This is run into the MS, or as you have written MS-MS. MS fragments compounds and they fragment in patterns that can identify families such as aldehydes etc. The main info given is the molecular ion (or rather a mass to charge ratio). In MS-MS, You can get fragmentation of the daughter ions resultant of the molecular ion which can further elucidate what the compound is.

MS is the gold standard of analytical detection

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How do you distinguish isotopes by mass spectrometer?

Isotopes can be distinguished by a mass spectrometer based on their differing atomic masses. The mass spectrometer ionizes a sample, separates the ions based on their mass-to-charge ratio, and then detects the abundance of each ion. The relative abundance of each isotope gives a unique mass spectrum that can be used to identify and quantify isotopes in a sample.


What instrument measures atomic mass?

A mass spectrometer is an instrument that measures the atomic mass of atoms and molecules. It does this by ionizing the sample and then separating the ions based on their mass-to-charge ratio. The resulting mass spectrum provides information on the relative abundance of different isotopes present in the sample.


How can isotpes of carbon be separated?

Mass spectrometer. (and centrifuges)


Which quantity is not required in order to calculate the mass of an ion using a mass spectrometer?

To calculate the mass of an ion using a mass spectrometer, the specific charge of the ion is not required. The mass-to-charge ratio (m/z) is measured directly, allowing for the determination of mass when the charge state is known. However, knowing the exact charge is not essential for calculating the mass itself, as the mass spectrometer provides the m/z value directly.


What is a Gas Chromatography-Mass Spectrometer?

A Gas Chromatography-Mass Spectrometer (GC-MS) is an analytical instrument used to separate and identify chemical compounds in a mixture. The gas chromatography component separates the compounds based on their physical properties, while the mass spectrometer identifies the compounds based on their mass-to-charge ratio. This powerful technique is commonly used in forensics, environmental analysis, and drug testing.

Related Questions

What is the device used to determine atomic masses?

A mass spectrometer is a device used to determine atomic masses by separating and measuring the mass-to-charge ratio of ions. By analyzing the deflection of ions in a magnetic or electric field, the mass spectrometer can provide accurate measurements of atomic masses.


How do you distinguish isotopes by mass spectrometer?

Isotopes can be distinguished by a mass spectrometer based on their differing atomic masses. The mass spectrometer ionizes a sample, separates the ions based on their mass-to-charge ratio, and then detects the abundance of each ion. The relative abundance of each isotope gives a unique mass spectrum that can be used to identify and quantify isotopes in a sample.


What instrument measures atomic mass?

A mass spectrometer is an instrument that measures the atomic mass of atoms and molecules. It does this by ionizing the sample and then separating the ions based on their mass-to-charge ratio. The resulting mass spectrum provides information on the relative abundance of different isotopes present in the sample.


How do you determine the mass of atom using mass spectrometer?

Actually in mass spectrometer the isotopes of an element are separated by applying magnetic field.Each isotope is then compared with carbon-12 to get the atomic mass of that isotope.


What rhymes with mass spectrometer?

Das Volkswagen?


Is difference of mass number is calculated by electron microscope?

no, the mass spectrometer.


How did the mass spectrometer advance the periodic table?

Using mass spectrometer, one can identify and/or separate the isotopes of the elements and also predict its composition in a given mixture.


What is the difference between Aston's mass spectrograph and Dempster's mass spectrometer?

Aston's mass spectrograph is a magnetic sector mass spectrometer that separates ions based on their mass-to-charge ratio using magnetic and electric fields. Dempster's mass spectrometer is an early design of a mass spectrometer that used electric and magnetic fields to separate ions based on their mass-to-charge ratio. Aston's design was an improvement over Dempster's, offering higher resolution and precision in analyzing isotopic composition.


What matter is a mass spectrometer used to get information from?

plants


How can isotpes of carbon be separated?

Mass spectrometer. (and centrifuges)


What is used to measure amounts of isotopes?

mass spectrometer


Which quantity is not required in order to calculate the mass of an ion using a mass spectrometer?

To calculate the mass of an ion using a mass spectrometer, the specific charge of the ion is not required. The mass-to-charge ratio (m/z) is measured directly, allowing for the determination of mass when the charge state is known. However, knowing the exact charge is not essential for calculating the mass itself, as the mass spectrometer provides the m/z value directly.