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What happens with demyelination and denervation?

Demyelination is the loss of the protective covering (myelin sheath) around nerve fibers, which can lead to impaired nerve conduction. Denervation refers to the loss of nerve supply to a particular muscle or organ, which can result in muscle weakness or dysfunction. Both conditions can lead to a variety of neurological symptoms depending on the location and extent of the damage.


What is the neuronal basis of denervation hypersensitivity?

Denervation hypersensitivity occurs in multiple sclerosis. In multiple sclerosis demyelination of oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system result in disruption of communication between upper motor neurons in the brain and the lower motor neurons in the gray matter of the spinal cord. The end result is denervation hypersensitivity with physical symptoms of increased muscle tone, difficulty controlling muscles, exaggerated reflexes, and muscle spasms.


What does disuse mean?

disuse means: no longer in use, obsolete. It can also refer to neglect please see related link


Can adaptation s occur throuh use and disuse?

Yes, the concept of adaptation through use and disuse was proposed by Jean-Baptiste Lamarck. He suggested that organisms could pass on acquired traits from use or disuse of certain organs to their offspring. However, this idea has been largely discredited in modern biology, as adaptation is primarily driven by natural selection acting on genetic variations.


Example of disuse theory under retention?

Disuse theory in memory retention suggests that information which is not rehearsed or practiced over time will fade away from memory. For example, if a person learns a new language but does not use it regularly, they may forget the vocabulary and grammar rules due to disuse. This theory highlights the importance of continuous practice and application in order to retain information in memory.