Denaturation
Enzymes are proteins, and proteins are designed to exist at specific temperatures and pH levels. When the temperature or the pH of their environment changes, the interactions that hold the amino acids of the enzyme in its particular conformation cease to function. The protein simply "falls apart" into an unstructured assembly of amino acids (a polypeptide still, but no longer a true protein) and cannot fulfill its function; this is called denaturation. For most enzymes, this occurs with an increase in temperature or a decrease in pH from their standard physiological environment.
The proteasome is responsible for degrading and recycling intracellular proteins that are damaged or no longer needed. This process helps to maintain cellular homeostasis by preventing the accumulation of misfolded or dysfunctional proteins.
Weather,more rain,longer droughts.
The ability to hold heat is called thermal inertia. This is the capacity of a material to resist changes in its temperature when heat is added or removed. Materials with high thermal inertia can maintain their temperature for longer periods of time.
when a doctor or radiologist looks at a xray or scan of a joint or bone then he understand the way it is supposed to be configured to work correctly. if he easily recognises that the shape in the joints are no longer as they should be or if growths have speared that indicates changes.
Proteins are polymers formed from amino acids. This term generally refers to chains longer than 50 amino acids, shorter chains are usually called polypeptides (or polypeptide chains).
Plasma outside of capillaries is no longer called plasma, its name changes to interstitial fluid.
Most proteins including enzymes are very sensitive to heat. When heated it will break the bonds that give the protein its shape. The protein only functions because of its shape. So when we heat a protein/enzyme, it changes its shape and it no longer functions. This process is called denaturation.
Denaturation
As we age, the proteins in the lens of the eye can degrade and become less flexible, leading to a condition called presbyopia. This results in difficulty focusing on close objects and can make the lens feel like it is no longer as firm or resistant to changes in shape. Age-related changes in the muscle that surrounds the lens can also affect its ability to change shape for focusing, causing the lens to feel looser.
When allele frequency changes, a population is said to no longer be in genetic equilibrium.
Making proteins and mitosis.
Changes in economy happen. The jobs that people have may no longer exist even after the recovery of the economy. In terms of employment, this is called economic dislocation.
Changes in tactics- a frontal assault was no longer a good tactic.
he discovered how sharks survive longer then they are supposed to
Blame global warming, enviormental changes, production/packaging changes.