The choices for this question were as follows:
The answer is option 4.
The binding of a hormone to a receptor is the first step. Target cell activation by hormone-receptor interaction depends equally on 3 factors. First the blood levels of the hormone, second ,relative numbers of receptors for that hormone on or in the target cells and the third ,strength of the binding between the hormone cell and the receptors.
Hormones do not bind to receptors with high capacity. The major defining properties of a hormone-receptor interaction, and what determines the strength of response is binding affinity and efficacy.
Hormone receptor
Hormone binding sites are specialized regions on target cells that specifically interact with hormones, facilitating communication between the endocrine system and various tissues. When a hormone binds to its respective receptor at these sites, it triggers a cascade of biochemical reactions that influence cellular activities, such as metabolism, growth, and immune responses. This binding is crucial for maintaining homeostasis and regulating physiological processes throughout the body.
Yes, the responsiveness of cells to hormones is determined by the presence of specific hormone receptor proteins on the cell surface or inside the cell. When a hormone binds to its corresponding receptor, it triggers a cellular response. Cells without the specific receptor for a hormone are not able to respond to that hormone.
Hormone and receptor interactions are based on specific binding between the hormone and its receptor. The receptor acts as a target for the hormone, triggering a series of cellular responses once bound. This interaction is highly specific, allowing for precise signaling within the body.
Protein synthesis is not a factor required for target cell activation by hormone receptor interaction. The essential factors include binding of the hormone to its receptor, conformational changes in the receptor, and activation of intracellular signaling pathways.
The binding of a hormone to a receptor is the first step. Target cell activation by hormone-receptor interaction depends equally on 3 factors. First the blood levels of the hormone, second ,relative numbers of receptors for that hormone on or in the target cells and the third ,strength of the binding between the hormone cell and the receptors.
The membrane protein responsible for binding hormones that can switch on a cell's response is typically a hormone receptor. These receptors are often found on the surface of the cell membrane and can activate signaling pathways inside the cell in response to hormone binding.
The binding of a signaling molecule, such as a hormone or neurotransmitter, to its respective receptor on the cell membrane represents the receipt of an intercellular signal. This binding triggers a cascade of events inside the cell, leading to a cellular response.
chaperone proteins (chaperonins)
A molecule such as a neurotransmitter or hormone that binds to a receptor is called a ligand. This binding triggers a biological response in the target cell, influencing its function.
I'm assuming you're asking what would happen if a receptor did not bind the proper hormone. The answer is a complex one because binding to a receptor does not necessarily mean that the receptor will be activated. Sometimes binding causes receptor inhibition; other times it can mean that the properties of the receptor change so that other hormones have an easier/harder time binding and activating it. But for the sake of giving an answer, let's say that we want to know what happens if a hormone binds and activates the wrong receptor. That answer is a relatively simple one: in most cases, the same events would take place that normally happen when the correct hormone binds the receptor. Let's take an example of a relatively uncommon cause of hypertension called hypertension exacerbated in pregnancy. In this condition, there's a mutation in the receptor for the hormone aldosterone that allows other hormones besides aldosterone (eg, progesterone) to bind it and activate it. When progesterone levels are high, as in pregnancy, the extra progesterone binds and heavily activates the aldosterone receptor, and the receptor essentially "thinks" that aldosterone has bound. So the action of progesterone at the aldosterone receptor are the same as aldosterone itself; since aldosterone is a major contributor to blood pressure, blood pressure increases to very high levels.
The shape of hormone receptors is crucial because it determines the binding specificity between the hormone and the receptor. When a hormone attaches to its specific receptor, it triggers a signaling cascade that regulates various physiological processes in the body. The specific shape ensures that only the correct hormone can bind to the receptor, leading to a specific biological response.
The first step in epinephrine signaling is the binding of epinephrine to its receptor on the cell membrane, typically a G protein-coupled receptor. This binding initiates a cascade of intracellular signaling events that ultimately lead to the desired physiological response.
each hormone receptor only binds to one hormone
Hormones do not bind to receptors with high capacity. The major defining properties of a hormone-receptor interaction, and what determines the strength of response is binding affinity and efficacy.