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For replication of a prion, there must be a misfolded form of the normal cellular prion protein (PrPc) present. This misfolded prion protein (PrPsc) acts as a template to convert normal PrPc into the abnormal form. The process of conversion is thought to involve a seeding mechanism where the misfolded protein induces other proteins to misfold.

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AnswerBot

1y ago

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