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The protein binding of tenedazole, an antifungal medication, is low, around 35-54%. This means that a significant portion of the medication remains free and active in the bloodstream for its therapeutic effects.

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1y ago

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The region of a protein that binds a ligand?

The region on a protein that binds a ligand is known as the binding site. This site is typically composed of specific amino acids that interact with the ligand through various chemical bonds and molecular interactions. The binding of the ligand to the protein's binding site is crucial for the protein's function and activity.


What is a G protein?

G protein is one of a number of guanosine triphosphate (GTP)-binding, regulatory proteins that serve as membrane-bound transducers of chemically and physically coded information; they are intermediaries in transmembrane signaling pathways that consist of three proteins: receptor, G protein, and effector. The G protein becomes activated upon binding GTP. The latter is subsequently slow hydrolyzed to GDP. When the hydrolysis is complete, the regulatory effect of the G protein is terminated and it is then available for reactivation by binding GTP.


Can mercuric chloride denature protein?

Yes, mercuric chloride can denature proteins by disrupting their structure through binding to thiol groups present in amino acids such as cysteine. This binding can lead to protein misfolding and loss of function.


What biological toxin acts by inhibiting DNA replication and protein synthesis?

Ricin is a biological toxin that acts by inhibiting protein synthesis by binding to the ribosomes and halting protein production.


What turns off transcription by binding to the operator?

A repressor protein turns off transcription by binding to the operator region. By binding to the operator, the repressor prevents the RNA polymerase from binding to the promoter region and initiating transcription. This prevents the expression of the gene or genes downstream of the operator.