The only real difference is the salt from which the medicine is derived. Betahistine dihydrochloride comes from a dihydrochloride salt, and mesilate comes from a mesilate salt.
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Potential difference.
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BetahistineBetahistine hydrochloride is the generic name for the anti vertigo drug SERC. It was first registered in Europe in 1970 for the treatment of Ménière's disease. It is commonly prescribed for people who have balance disorders or to alleviate the vertigo symptoms associated with Ménière's disease.Betahistine is available in 8mg or 16mg tablets taken 3 times daily. Doses may be adjusted to between 24-48mg a day as needed. It is contraindicated for people with peptic stomach ulcers or tumours of the adrenal gland. People with bronchial asthma should be closely monitored.Chemistry and PharmacokineticsBetahistine chemically is 2-[2-(methylamino) ethyl] pyridine, and is formulated as the dihydrochloride salt. Is is as close resembling between the structures of betahistine and histamine.Betahistine comes in a tablet form and should be taken orally. It is rapidly and completely absorbed from its tablet form. The mean plasma half-life is 3-4 hours, and excretion is virtually complete in the urine within 24 hours. Plasma protein binding is very low.The metabolism of betahistine produced two inactive metabolites, pyriylacetic acid and 2-(2-aminoethyl) pyridine.
The active ingredient in both pills is the same (Cetirizine). The difference between hydrochloride and dihydrochloride is the difference between the non active ingredients in the pills that are added to the drug so that there is enough bulk to make a pill. The above 'advice' is simply rubbish. Any (old Skool) A-Level chemistry student knows the difference between 'hydrochloride' and 'di-hydrochloride': Not the same molecule.However, in layman's terms: cetirizine di-hydrochloride is the real thing and is less likely to make you drowsy. Cetirizine hydrochloride is a copycat molecule to work around patent laws.From personal experience, cetirizine hydrochloride makes me drowsy, whereas cetirizine di-hydrochloride does not. :-)
Yes, aspirin can generally be taken with betahistine, as there are no known direct interactions between the two medications. However, it is always important to consult with a healthcare provider before combining any medications to ensure safety and effectiveness based on individual health conditions. Additionally, consider any potential side effects or underlying health issues that may affect your decision.
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The difference between a shogun and a samurai is like the difference between a king and a knight.
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