Assay is the quantitative determination of the amount of a component in a sample.
Purity is the determination of the impurities in the sample. It can be quantitative, semi-quantitative or qualitative.
For example : if you dissolve 4 grams of compound A (with no impurities in it) in 6 grams of water, you get a solution of compound A with 100% purity and 40% assay.
From the ICH Guideline Q2A (Validation of Analytical methods) :
"- Testing for impurities can be either a quantitative test or a limit test for the impurity in a sample. Either test is intended to accurately reflect the purity characteristics of the sample. [...]
- Assay procedures are intended to measure the analyte present in a given sample. In the context of this document, the assay represents a quantitative measurement of the major component(s) in the drug substance."
assay on as is basis includes the sample+water content+residual solvents+others. but assay on as is basis takes water content into account that means weight of the water present in the sample will be added in weighing the sample quantity of API required.
An assay is a scientific test or analysis used to measure the presence, amount, or activity of a substance or compound in a sample. Assays are commonly used in biology, chemistry, and medicine to study a wide range of biological and chemical processes.
they are both incredibly boring so no there is no difference ;)
In biochemistry, an endpoint assay measures the final amount of a product formed or substrate remaining after a reaction has stopped, providing a single data point. A kinetic assay, on the other hand, measures the rate of a reaction by recording multiple data points over time. Kinetic assays provide additional information about reaction mechanisms, enzyme activity, and inhibitor kinetics compared to endpoint assays.
No, assay by mass balance and assay by as is basis are not equivalent. Assay by mass balance calculates the amount of a component based on material balance equations, while assay by as is basis measures the amount of a component without accounting for any changes or losses that may occur during processing.
Inter-assay variability refers to differences in results between different tests, while intra-assay variability refers to variations within the same test.
what is the difference between product analysis and heat analysis
what is difference between accounts and engineering
manufacturing process of steel plates difference between heat and product analysis ?
assay on as is basis includes the sample+water content+residual solvents+others. but assay on as is basis takes water content into account that means weight of the water present in the sample will be added in weighing the sample quantity of API required.
manufacturing process of steel plates difference between heat and product analysis ?
Assay on 'as is' basis refers to the composition of a substance including its water content, while assay on 'dried' basis refers to the composition of a substance after removing the water content. Comparing these two types of assays can help in understanding the true chemical composition of a substance excluding the influence of water content.
Difference between e-resuming system of bdjobs and phrotom alo.com
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There is no difference.AOV = Analysis of VarianceANOVA = Analysis of Variance.
no different it's the same