assay on as is basis includes the sample+water content+residual solvents+others. but assay on as is basis takes water content into account that means weight of the water present in the sample will be added in weighing the sample quantity of API required.
1. anhydrous means : Means remove the water content & solvent free value calculated in the assay. 2. On dry base : Means remove the loss on dry & solvent free value calculated in the assay
No, assay by mass balance and assay by as is basis are not equivalent. Assay by mass balance calculates the amount of a component based on material balance equations, while assay by as is basis measures the amount of a component without accounting for any changes or losses that may occur during processing.
Anhydrous basis refers to expressing the concentration of a substance without considering any water present in the sample. It is commonly used in chemistry to provide a more accurate representation of the actual concentration of the substance of interest. By expressing values on an anhydrous basis, any water content in the sample is excluded from the calculations.
An assay on a dry basis refers to expressing the concentration of a substance in a sample after removing the moisture content. This method is commonly used in analytical chemistry to provide a more accurate representation of the actual substance content in a sample by eliminating the variability introduced by water content.
On the basis of plastids a plant cell can be recognized from animal cell. The plant cells have several plastids including chloroplasts. Animal cells are characterized by their abscence.
1. anhydrous means : Means remove the water content & solvent free value calculated in the assay. 2. On dry base : Means remove the loss on dry & solvent free value calculated in the assay
To calculate the assay of Ceftriaxone sodium BP on an anhydrous basis, you first need to determine the molecular weight of Ceftriaxone sodium. Next, you would divide the weight of the anhydrous Ceftriaxone sodium by the total weight of the sample and multiply by 100 to get the percentage on an anhydrous basis. This calculation helps ensure accurate dosing and purity of the compound.
Assay on 'as is' basis refers to the composition of a substance including its water content, while assay on 'dried' basis refers to the composition of a substance after removing the water content. Comparing these two types of assays can help in understanding the true chemical composition of a substance excluding the influence of water content.
No, assay by mass balance and assay by as is basis are not equivalent. Assay by mass balance calculates the amount of a component based on material balance equations, while assay by as is basis measures the amount of a component without accounting for any changes or losses that may occur during processing.
what is Difference between wholesaler and retailer on the basis risk?
Potency is the purity of the compound ;this states % available of the main component without water and residual solvents Assay is defined as Potency plus water and residual solvents and other remaining fractions please note assay can also be expressed as as is basis or dry basis Assay and Potency are same if assay is exprtessed as as is basis please note Potency word is mainly used for Antibiotics and bilogicals courtsey ; CDER , USFDA ; Dr.Uttam Krishna
xx.x% on a dried basis implies that the material will have had all possible liquid impurities (water, solvents, residual liquid chemicals) removed by the drying process.Let's call w% is % of (water content, solvents, and residual) all combine. Your as-is value would be:xx.x% * (100 - w%)% as-is = ---------------------100Hopes that help.
Anhydrous basis refers to expressing the concentration of a substance without considering any water present in the sample. It is commonly used in chemistry to provide a more accurate representation of the actual concentration of the substance of interest. By expressing values on an anhydrous basis, any water content in the sample is excluded from the calculations.
The main difference is that base is the literal word and basis the figurative word
both are same
To calculate the potency of a standard on an "as is" basis from an anhydrous and solvent-free basis, you need to take into account the moisture and solvent content in the standard. First, determine the percentage of water and solvent in the standard. Then, adjust the potency by factoring in the moisture and solvent content to arrive at the potency on an "as is" basis. This ensures that you are accurately reflecting the concentration of the active ingredient in the standard.
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