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What is the effect of dopamine on the cells of the GPi?

Updated: 11/4/2022
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GaleEncyofSurgery

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13y ago

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The effect of dopamine on the cells of the GPi is to suppress them by preventing them from firing.

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Q: What is the effect of dopamine on the cells of the GPi?
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How does the pallidotomy procedure mimic the effect of dopamine?

Pallidotomy mimics this action by permanently destroying the GPi cells.


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These symptoms are due to degeneration of a small portion of the brain called the substantia nigra, the cells of which secrete the chemical dopamine that influences cells in another brain region called the globus pallidus internus (GPi).


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