If the action of acetylcholinesterase wereinhibited, the level of acetylcholine would increase as well as the duration of its action. The effect would cause muscle spasms.
This is because an electrical signal, or nerve impulse, is conducted byacetylcholine across the junction between the nerve and the muscle (the synapse) stimulating the muscle to move. Normally, after the appropriate response is accomplished, acetylcholinesterase is released which breaks down the acetylcholine terminating the stimulation of the muscle. The enzyme acetylcholine accomplishes this by chemically breaking the compound into other compounds and removing them from the nerve junction.
If acetylcholinesterase is unable to breakdown or remove acetylcholine, the muscle can continue to move uncontrollably.
Electrical impulses can fire away continuously unless the number of messages being sent through the synapse is limited by the action of acetylcholinesterase.
Repeated and unchecked firing of electrical signals can cause uncontrolled, rapid twitching of some muscles, paralyzed breathing, convulsions, and in extreme cases, death.
Once acetylcholine (ACh) binds to its receptor, it can either stimulate or inhibit the activity of the cell. This activation triggers a cellular response, such as muscle contraction or nerve cell communication. After its action, ACh is rapidly broken down by the enzyme acetylcholinesterase to terminate the signal.
Ca2+
Calcium ions are the key chemicals involved in muscle contraction. When a muscle is stimulated, calcium is released from the sarcoplasmic reticulum within the muscle cell, leading to the sliding of actin and myosin filaments which results in muscle contraction. ATP is also required for the energy needed for muscle contraction.
The transverse (T) tubules are structures in a muscle cell's membrane that deliver signals from the cell surface to the sarcomeres, which are the contractile units of the muscle cell. These T-tubules help coordinate muscle contraction by allowing the signal for muscle contraction to penetrate deeply into the cell.
A Muscle Twitch is a single contraction of skeletal muscle. The three distinct phases are latent, contraction, and relaxation. Latent Phase: Is the interval from the stimulus application until the muscle begins to contract (shorten). Note that there is no traced activity during this phase, but there are some electrical and chemical changes taking place during this phase. Contraction Phase: This phase is when the muscle fibers shorten, the tracings will show during this phase (a) peak(s). Relaxation Phase: This phase is represented by the downward curve in your tracings, this is when the muscle is going back to its original state of relaxation and the muscle will once again lengthen
6 steps in a muscle contraction
The specific structure within a muscle cell that contains the sarcomere I band and is responsible for muscle contraction is called the myofibril.
Once acetylcholine (ACh) binds to its receptor, it can either stimulate or inhibit the activity of the cell. This activation triggers a cellular response, such as muscle contraction or nerve cell communication. After its action, ACh is rapidly broken down by the enzyme acetylcholinesterase to terminate the signal.
Ca2+
T-tubules in muscle cells help transmit electrical signals deep into the cell, allowing for coordinated muscle contraction.
T-tubules are structures in muscle cells that help transmit electrical signals for muscle contraction. They allow for the rapid spread of these signals throughout the cell, ensuring coordinated muscle fiber contraction.
T-tubules are invaginations of the cell membrane in skeletal muscle fibers that help transmit electrical signals deep into the muscle cell. This allows for the coordinated release of calcium ions from the sarcoplasmic reticulum, which triggers muscle contraction. In essence, t-tubules play a crucial role in linking the electrical stimulation of the muscle cell membrane to the contraction of the muscle fibers.
Calcium ions are the key chemicals involved in muscle contraction. When a muscle is stimulated, calcium is released from the sarcoplasmic reticulum within the muscle cell, leading to the sliding of actin and myosin filaments which results in muscle contraction. ATP is also required for the energy needed for muscle contraction.
The myofibril is the basic muscle cell, within which is the sarcomere, the basic unit of muscle contraction.
Mitochondria - to produce the ATP needed for muscle contraction
The transverse (T) tubules are structures in a muscle cell's membrane that deliver signals from the cell surface to the sarcomeres, which are the contractile units of the muscle cell. These T-tubules help coordinate muscle contraction by allowing the signal for muscle contraction to penetrate deeply into the cell.
Acetylcholine binds to the muscle cell membrane, causing a temporary rush of calcium ions into the muscle cell. This influx of calcium triggers muscle contraction.