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The main difference is that aerobic replenishment of energy occurs in the presence of oxygen, allowing for more efficient production of energy through processes like cellular respiration. In contrast, anaerobic replenishment of energy occurs in the absence of oxygen and is less efficient, relying on processes like glycolysis to produce energy quickly but with the byproduct of lactic acid buildup.

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Q: What is the main difference between aerobic and anaerobic replenishment of energy?
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