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"Disease" is any abnormal condition of a living organism; in common American English useage it typically refers to an infectious condition such as bacterial urinary tract infections or viral upper respiratory infections. "Farm animal" refers to any of several domesticated animals typically raised in some degree of confinement and dependent upon human intervention to provide food, water and shelter. In the United States, "farm animal" typically includes cattle, sheep, goats and pigs; horses have transitioned out of the "farm animal" category and are more commonly being seen as a separate category on their own.

Putting the terms back together, "farm animal disease" is any abnormal condition of any of the domesticated animals commonly associated with farming. This can range from a Salmonellaoutbreak in laying hens to E. coli mastitis in dairy cattle to a PRRS virus outbreak in farrowing sows.

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