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4-Aminonicotinic acid is one of the key synthetic intermediates of therapeutic drugs for cardiovascular and cerebrovascular diseases. There is a novel four-step synthesizing route of 4-aminonicotinic acid starting from isoquinoline and 3,4-pyridine dicarboxylic acid,and its overall yield of 4-aminonicotinic acid can be up to 30%(based on isoquinoline).

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