answersLogoWhite

0

An action potential can also be called a nerve impulse which is known to be stimulated by an external stimuli or upon internal excitation.

This action potential travels through a neuron and involves charged ions (the key ones are sodium ions and potassium ions) that cross the membrane barrier of the neuron.

In the longitudinal section of the axon of the neuron (the part that carries the signal which may be covered in Schwann cells to protect the it) the action potential cycle occurs.

There are four main stages: The Resting Membrane Potential, Depolarization, Repolarization, and the Refractory Period.

In the Resting Membrane Potential Stage there is an active force that maintains the resting membrane potential at -70 mV. This active force is the Sodium Potassium Pump where three sodium ions leave the nerve cell and two potassium ions enter. With the Sodium Potassium Pump, it transports these ions actively and so ATP is required. In addition to the Sodium Potassium Pump, there are voltage-sensitive potassium slow leak channels that are involved with passive transport and there are also voltage sensitive sodium gates that are passive sodium channels. They are normally impermeable to sodium however it can't pass through unless there is an electrical current to open it.

In the Depolarization Stage, an external stimuli occurs altering the tertiary structure of sodium gates allowing the nerve cell membrane to become more permeable to sodium than potassium. Therefore, sodium floods in passively making the extracellular fluid (ECF) more negative and the intracellular fluid (ICF). Now the voltage inside the cell is +50 mV compared to the previous stage where it was -70 mV.

Once the cell has reached a voltage of +50 mV, sodium gates close and so the inflow of sodium ions into the cell are discontinued. Because of the altered concentration gradient of ions in the Depolarization Stage, it causes the potassium channels to alter their shape. As a result, there is an inflow of potassium ions outside of the cell and the inside becomes negative again. This stage is known as the Repolarization Stage. This prevents the signal from going backwards. The voltage inside the cell is now at -80 mV.

In the last stage, Refractory Period, the Sodium Potassium Pump actively re-establishes the resting membrane potential. It takes time to reestablish the sodium and potassium concentrations to -70 mV.

Please note that depolarization cannot occur until the resting membrane potential is reached (-70 mV).

As an aside, the action potential follows the All or None Principle. This means that larger signals do not create larger action potentials. A neuron must always reach -70 mV before the signal is passed along a neuron. Therefore, the action potential will occur fully or not at all.

The action potential is an electrical event occurring when a stimulus of sufficient intensity is applied to a neuron or muscle cell, allowing sodium to move into the cell and reverse the polarity.

Normally neurones (neurons, or nerve cells) maintain a resting potential of -70mV across their membrane by the active pumping of 3Na+ ions out of the cell for every 2 K+ ions pumped into the cell by a Na+/K+ pump. When the neurone is stimulated, sodium ion channels open in the membrane and sodium ions flood in to the cell down an electrochemical gradient by diffusion, increasing the potential of the cell to +40mV. This is called depolarisation. At this point the sodium channels close, and potassium ion channels open. Potassium ions flood out of the cell down their electrochemical gradient, decreasing the cell's membrane potential. This is called repolarisation. There is a slight overshoot where too many potassium ions diffuse out of the cell, and there is hyperpolarisation where the cell's membrane potential falls below its normal -70mV, but this is corrected and the resting potential is once again restored. This is the sequence of events that makes up a single action potential. Action potentials are transmitted by saltatory conduction in the neurone, and impulses jump from node to node along the axon of the neurone.

User Avatar

Wiki User

14y ago

What else can I help you with?

Related Questions

What was the effect of curare on eliciting an action potential?

It creates an action potential


Will a hyperpolarization graded potential lead to an action potential?

No, hyperpolarization graded potentials do not lead to action potentials. Hyperpolarization makes the membrane potential more negative, which inhibits the generation of an action potential by increasing the distance from the threshold potential needed to trigger an action potential.


What is the regeneration of action potential called?

The regeneration of action potential is called "propagation." It involves the transmission of the action potential along the length of the neuron's axon.


Why does curare create an action potential?

Curare does NOT create an action potential. It binds to nicotinic acetylcholine receptors (which are primarily excitatory), and prevents the formation of an action potential.


Also called a nerve impulse transmitted by axons?

action potential


Why does curare appear to generate an action potential?

It doesn't. I prevents an action potential from forming.


What transmission of the depolarization wave along the neurons membrane?

Action potential


Can subthreshold stimulation cause an action potential?

No, subthreshold stimulation is not sufficient to trigger an action potential. The membrane potential needs to reach a certain threshold level for an action potential to be generated. Subthreshold stimulation only produces graded potentials that do not reach the threshold for firing an action potential.


What is the purpose of the political action committee?

The purpose is to support a issue or candidate with political action.


What is the difference between a compound action potential and a single action potential?

Single action potentials follow the "all or none" rule. That is, if a stimulus is strong enough to depolarize the membrane of the neuron to threshold (~55mV), then an action potential will be fired. Each stimulus that reaches threshold will produce an action potential that is equal in magnitude to every other action potential for the neuron. Compound action potentials do not exhibit this property since they are a bundle of neurons and have different magnitudes of AP's. Thus compound action potentials are graded. That is, the greater the stimulus, the greater the action potential.


What is by purpose?

A by-purpose is an indirect or incidental purpose for an object or an action.


What is a by-purpose?

A by-purpose is an indirect or incidental purpose for an object or an action.