According to the USP (United States Pharmacopeia), the hardness requirement for tablets is typically specified as a minimum force required to crush the tablet. This is often expressed in terms of kiloponds or newtons. The specific hardness requirement may vary depending on the formulation and purpose of the tablet.
The principle of tablet hardness is to measure the tablets' resistance to breaking or chipping under pressure, which is important for assessing their mechanical strength. The principle of tablet friability is to measure the tablets' tendency to break or crumble when subjected to mechanical stress during handling or storage, serving as an indicator of their robustness and quality. Both tests are crucial in assessing the physical properties of tablets for formulation and manufacturing.
USP method 905 "Uniformity of Dosage Units" describes how to calculate the weight variation for your dosage forms. If you need a copy of method simply drop me an email at waqassial@hotmail.com Regards
USP grade refers to a set of standards established by the United States Pharmacopeia for the purity, quality, strength, and consistency of drugs, food ingredients, and dietary supplements. Substances labeled as USP grade meet the specific criteria outlined in the USP-NF monographs.
Increasing tablet hardness without changing the formulation can be achieved by adjusting the compression force during tablet manufacturing. By increasing the compression force, the particles in the formulation will be more tightly packed together, resulting in harder tablets. Alternatively, using a smaller tablet punch size can also increase tablet hardness without altering the formulation.
According to the USP (United States Pharmacopeia), the hardness requirement for tablets is typically specified as a minimum force required to crush the tablet. This is often expressed in terms of kiloponds or newtons. The specific hardness requirement may vary depending on the formulation and purpose of the tablet.
Atenolol tablets USP is the treatment of hypertension, which is low blood pressure. Atenolol tablets UDL is what controls high blood pressure.
NMT 2%
average weight of tablets (mg) max. %age difference allow 130 or less (+)(-)10% 130 - 324 (+)(-)7.5% more than 324 (+)(-)5%
keep the hardness of the tablets b/w 4-6 kg/(cm)2 using pfizer or monsento apparatus
Estratest H.S. is the half-strength version of the Estratest product of Solvay Pharmaceuticals, Inc. The medication is dispensed as oval, hard tablets, colored light green and labeled "SOLVAY 1023". The tablets are provided to pharmacists in bottles of 100 or 1000. Each tablet contains 0.625 mg of Esterified Estrogens, USP and 1.25 mg of Methyltestosterone, USP.
BP - British Pharmacopoeia and USP - United States Pharmacopeia.In the world there are various pharmacopeias which are guidelines for the Pharmaceutical Industry for manufacture and testing of drugs. BP and USP are two of approximately 30 country or region run pharmacopeias. In the BP and USP there are specific tests which must be followed to be labeled BP or USP and depend on which drug (aspirin, acetominophen, etc) is being tested. In the US, it is a legal requirement that all drugs meet or exceed the USP. In various other places the laws may not be as strict to where any pharmacopeia may be used (British, Canadian, Japanese, US, European etc).
What are the advantage of the USP?
what is usp of allahabad bank
The principle of tablet hardness is to measure the tablets' resistance to breaking or chipping under pressure, which is important for assessing their mechanical strength. The principle of tablet friability is to measure the tablets' tendency to break or crumble when subjected to mechanical stress during handling or storage, serving as an indicator of their robustness and quality. Both tests are crucial in assessing the physical properties of tablets for formulation and manufacturing.
USP method 905 "Uniformity of Dosage Units" describes how to calculate the weight variation for your dosage forms. If you need a copy of method simply drop me an email at waqassial@hotmail.com Regards
USP stands for unique selling proposition.