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Blood is primarily warmed through conduction, a process in which heat is transferred through direct contact. As the blood passes through the capillaries inside the muscles and internal organs, it is heated through conduction by the warmer surrounding tissues.

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The warm blood then passes through the capillaries in the skin and the alveoli of the lungs. These tissues are usually cooler because one surface of the tissue is in contact with the air. Consequently, the blood cools as it passes through these capillaries.

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The body regulates the core temperature by constantly adjusting the flow of blood through the muscles and organs (especially the liver) to control the rate of heat transfer from those tissues into the blood, and also by managing the flow of the blood through the skin to control the rate of heat transfer from the blood into the cooler skin tissue.

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