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Ground substance is located within the extracellular matrix of connective tissue. It fills the space between cells and fibers and provides support, lubrication, and a pathway for nutrient exchange. Ground substance is mainly composed of water, proteoglycans, glycoproteins, and other molecules.

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1y ago

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Matrix is the extracellular material produced by cells and is composed of fibers and ground substance. Ground substance is the non-cellular component of the matrix and consists of water, glycoproteins, and proteoglycans. Matrix provides structural support and organization, while ground substance serves as a medium for the exchange of nutrients and waste between cells and the bloodstream.


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No, extracellular fluid and ground substance are two different components found in tissues. Extracellular fluid is the fluid found outside of cells in the body, while ground substance is a gel-like substance present in the extracellular matrix that contains water, ions, and macromolecules like proteoglycans and glycoproteins.


What is the medium through which nutrients diffuse?

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Common polysaccharides found in ground substance include hyaluronic acid, chondroitin sulfate, and keratan sulfate. These polysaccharides help contribute to the gel-like consistency of ground substance and play a role in maintaining tissue hydration and resilience.


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