Blood cell
The mutation must be present in the egg cell (oocyte) of the woman in order for it to be passed on to her offspring. Sperm cells from the father do not contain the cytoplasm that would carry the mutation.
Germ cells, specifically eggs and sperm, must have a mutation in order for it to potentially be passed on to offspring. These mutations can occur during the process of cell division that produces these specialized reproductive cells. Any mutation that arises in somatic cells (non-reproductive cells) will not be passed on to offspring.
Mutations that occur in somatic cells, such as skin or muscle cells, are not passed on to offspring because they do not affect the genetic material in sperm or egg cells. Only mutations that occur in germ cells, which are involved in forming eggs or sperm, can be passed on to offspring.
The gametes (sex cells): sperm and egg.
How traits are passed to offspring
The mutation must be present in the egg cell (oocyte) of the woman in order for it to be passed on to her offspring. Sperm cells from the father do not contain the cytoplasm that would carry the mutation.
Germ cells, specifically eggs and sperm, must have a mutation in order for it to potentially be passed on to offspring. These mutations can occur during the process of cell division that produces these specialized reproductive cells. Any mutation that arises in somatic cells (non-reproductive cells) will not be passed on to offspring.
The mutation must be present in the Reproductive cell, Ovum/Egg in females (present in the Ovary) and Sperm in males.
Mutations that occur in somatic cells, such as skin or muscle cells, are not passed on to offspring because they do not affect the genetic material in sperm or egg cells. Only mutations that occur in germ cells, which are involved in forming eggs or sperm, can be passed on to offspring.
A mutation in a gene can happen by addition, deletion or substitution of base pairs. This means that the order of the bases will change- a new base may be added, a base may be lost, or one base may be substituted for another. The result of these mutations is that it causes the DNA to code for a different protein. If a mutation occurs in a sex cell, the mutation can be passed on to an offspring and affect the offspring's phenotype.
A mutation in a gene can happen by addition, deletion or substitution of base pairs. This means that the order of the bases will change- a new base may be added, a base may be lost, or one base may be substituted for another. The result of these mutations is that it causes the DNA to code for a different protein. If a mutation occurs in a sex cell, the mutation can be passed on to an offspring and affect the offspring's phenotype.
The gametes (sex cells): sperm and egg.
Community
How traits are passed to offspring
CS is inherited in an autosomal recessive pattern. In order for a child to be affected by CS, he or she must inherit a mutation (-) in the same CS gene from both parents. The parents and other "carriers" of a single CS gene mutation remain healthy. Once a couple are known to carriers, they have a 1 in 4 (25%) chance of having another child with CS. http://www.cockaynesyndrome.net/main/AboutCS.aspx
An Inversion mutation is a mutation that causes a reversal in the order of a segment of a chromosome within the chromosome, or a gene.
A mutation.