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If a strand of DNA with the sequence TGA mutated to GCA would it be a silent or missense mutation?
Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will. Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.
How many amino acids would this protein have if a mutation occurred and the 7th dna base pair of the dna strand was changed from a-t to t-a?
This mutation would cause a frameshift mutation, shifting the reading frame of the DNA sequence. Most likely, this would lead to a completely different protein being translated, resulting in a protein with a different sequence of amino acids from the original protein. The number of amino acids would depend on the specific changes in the protein sequence caused by the frameshift mutation.
What change to this sequence would indicate a silent mutation?
A silent mutation occurs when a change in the DNA sequence does not alter the amino acid sequence of the resulting protein. This can happen through a substitution of a nucleotide that still codes for the same amino acid due to the redundancy of the genetic code. For example, if the original sequence is "GAA" (which codes for glutamic acid) and it changes to "GAG," this would represent a silent mutation since both codons code for the same amino acid. Thus, the change in the sequence that doesn't affect the protein's amino acid sequence indicates a silent mutation.
Why is point mutation dangerous?
A frame shift mutation destroys the correct sequence of amino acids from the point of the mutation. The protein produced by a frame shift mutation would more than likely be nonfunctional.
How is it possible for gene with a mutation in coding region to encode a polypeptide with the same amino acid sequence as the nonmutant gene?
If the mutant codon still codes for the same amino acid (a silent mutation). For example: GUU, GUC, GUA and GUG all code for the amino acid Valine. So if the mutation changed the codon from GUU to GUA - Valine would still be produced and therefore the polypeptide will be identical.
What One example of a mutation that would not affect an organisms phenotype?
A silent mutation is an example of a mutation that would not affect an organism's phenotype. This type of mutation occurs in a non-coding region of DNA, such as an intron, and does not change the amino acid sequence of the protein produced. Therefore, it has no impact on the organism's outward appearance or characteristics.
If a strand of DNA with the sequence TGA mutated to GCA would it be a silent or missense mutation?
Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will. Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.
How many amino acids would this protein have if a mutation occurred and the 7th dna base pair of the dna strand was changed from a-t to t-a?
This mutation would cause a frameshift mutation, shifting the reading frame of the DNA sequence. Most likely, this would lead to a completely different protein being translated, resulting in a protein with a different sequence of amino acids from the original protein. The number of amino acids would depend on the specific changes in the protein sequence caused by the frameshift mutation.
Why does an insert mutation usually cause more defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
What change to this sequence would indicate a silent mutation?
A silent mutation occurs when a change in the DNA sequence does not alter the amino acid sequence of the resulting protein. This can happen through a substitution of a nucleotide that still codes for the same amino acid due to the redundancy of the genetic code. For example, if the original sequence is "GAA" (which codes for glutamic acid) and it changes to "GAG," this would represent a silent mutation since both codons code for the same amino acid. Thus, the change in the sequence that doesn't affect the protein's amino acid sequence indicates a silent mutation.
What happens if only one amino acid is coded incorrectly?
If only one amino acid is coded incorrectly in a protein sequence, it may result in a missense mutation. This could potentially lead to a change in the structure and function of the protein. The impact of the mutation would depend on the specific amino acid involved and its location within the protein.
Why is a silent mutation called silent?
a mutation that does not affect protein production.
Why is point mutation dangerous?
A frame shift mutation destroys the correct sequence of amino acids from the point of the mutation. The protein produced by a frame shift mutation would more than likely be nonfunctional.
Which mutation would not change the remainder of the reading frame of a gene sequence that follows the mutation?
A silent mutation, where a nucleotide substitution results in a codon that codes for the same amino acid, would not change the remainder of the reading frame of a gene sequence. This is because the amino acid sequence produced by the altered codon remains the same.
How is it possible for gene with a mutation in coding region to encode a polypeptide with the same amino acid sequence as the nonmutant gene?
If the mutant codon still codes for the same amino acid (a silent mutation). For example: GUU, GUC, GUA and GUG all code for the amino acid Valine. So if the mutation changed the codon from GUU to GUA - Valine would still be produced and therefore the polypeptide will be identical.
Why does a deletion mutation usually cause more defects during protein synthesis than a point mutation?
Deletion mutations can affect the entire base sequence.
If a codon is mutated say from GGU to CGU is the same amino acid specified?
Yes. GGU specifies Glycine and CGU specifies Arginine.
