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Maldi-TOF (Matrix-Assisted Laser Desorption/Ionization Time-of-Flight) Mass Spectrometry was introduced by Koichi Tanaka and Franz Hillenkamp in the late 1980s. Their work revolutionized the field of mass spectrometry by allowing for rapid and sensitive analysis of biomolecules like proteins and peptides.

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Where the maldi-tof used?

MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight) mass spectrometry is commonly used in biochemistry, medicine, and microbiology for rapid and accurate identification of proteins, peptides, DNA, and microorganisms. It is used in various applications, such as clinical diagnostics, proteomics research, and microbial identification in laboratories.


What are the techniques used to identify microorganisms in industries?

Techniques used to identify microorganisms in industries include culture-based methods, where samples are grown on selective media to isolate specific organisms. Molecular methods, such as polymerase chain reaction (PCR) and DNA sequencing, allow for precise identification by analyzing genetic material. Additionally, rapid diagnostic techniques like enzyme-linked immunosorbent assays (ELISAs) and mass spectrometry (e.g., MALDI-TOF) provide quick identification based on protein profiles or antigen-antibody reactions. These methods are crucial for quality control, contamination monitoring, and ensuring safety in food, pharmaceutical, and biotechnology sectors.


What job does the nucleus do in a nerve cell?

Nucleus - contains genetic material (chromosomes) including information for cell development and synthesis of proteins necessary for cell maintenance and survival. Covered by a membrane.


How was Mount Pelee born?

Mount Pelee is a stratovolcano. It is made of layers of ash and lava flows from past volcanic eruptions. The volcano itself formed as a result of a process called subduction. The the east, a portion of the North American Plate is colliding with and sliding under the Caribbean Plate. As it sinks into the mantle it takes some water with it. This water alters the chemistry of the hot rock of the mantle, causing some of it to melt and rise through the crust.


How is the landscape of venus different from the landscape of earth?

The Jovian atmosphere consists of 75% Hydrogen, 24% Helium and >1% other elements. It is entirely comprised of gas, there is no solidity to it whatsoever. The surface is just enormous hurricane-like storms of gases swirling infinitely. It would be quite violent and turbulent if a human was capable of experiencing the surface of Jupiter (which they are not). Imagine thousands upon thousands of hurricanes all hundreds and thousands tof times more powerful than the most powerful storms we see on Earth, and that is the landscape of Jupiter 24 hours a day, 7 days a week. Signed, -C (Actually, it would be 10 hours per day and weeks would be about 28(?) times longer... but you get the idea.)

Related Questions

Where the maldi-tof used?

MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight) mass spectrometry is commonly used in biochemistry, medicine, and microbiology for rapid and accurate identification of proteins, peptides, DNA, and microorganisms. It is used in various applications, such as clinical diagnostics, proteomics research, and microbial identification in laboratories.


Why trifluroacetic acid is used in MALDI -TOF?

TFA provides assistance in ionisation in the matrix, providing both ions and absorption at the wavelength of the MALDI laser.


What is the tof?

"ToF" typically stands for "Time of Flight," a measurement used in various fields, including physics and engineering, to determine the time it takes for an object or signal to travel a specific distance. In applications like time-of-flight mass spectrometry, it helps analyze the mass of particles based on their travel time through a vacuum. ToF can also refer to technologies like ToF cameras, which measure distances by calculating the time it takes for light to return from a surface after being emitted.


What are proteomic tools and their applications?

proteomics tools are basically used for protein structure determination and analysis. proteomic tools includes, mass spectometry, NMR, terminater and traitor technology, quadrupole analyzer, MALDI-TOF.


What is the use of TOF in massspectrometer?

The ToF is the mass separator, distinguishing ions by their mass in the same way as the magnetic sector does in a magnetic sector mass spec.


How do you measure midazolam metabolites in urine?

Midazolam metabolites in urine can be measured using techniques like gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass spectrometry (LC-MS/MS). These methods can accurately detect and quantify specific metabolites of midazolam to assess drug metabolism and clearance in the body.


What are the techniques used to identify microorganisms in industries?

Techniques used to identify microorganisms in industries include culture-based methods, where samples are grown on selective media to isolate specific organisms. Molecular methods, such as polymerase chain reaction (PCR) and DNA sequencing, allow for precise identification by analyzing genetic material. Additionally, rapid diagnostic techniques like enzyme-linked immunosorbent assays (ELISAs) and mass spectrometry (e.g., MALDI-TOF) provide quick identification based on protein profiles or antigen-antibody reactions. These methods are crucial for quality control, contamination monitoring, and ensuring safety in food, pharmaceutical, and biotechnology sectors.


What are some common laboratory techniques use in?

There are unlimited answers to your question. Here I will name some. 1) Thermo-cycler and PCR. To amplify a small sample of DNA. 2) MALDI-TOF or Quad Ion Trap-TOF Mass spectrometer. This equipment can help determine, identify, and characterize the protein found in the unknown sample. 3) Flowcytometer. :) A super machine use to count, sort, identify amount of cells in the sample. 4) hemocytometer. Count cells, (without the sorting function) 5) Micro Array system. This piece of equipment can array a sample. Can be use in DNA micro array or other protein micro array. :) Identify protein that is present. 6) Genetic Analysis System. This piece of baby is use for sequencing genes. 7) High Powered Liquid Chromatography system / Gas Chromatography-Mass Spectrometer. Identify chemical present in sample. Able to analyse mass sample, chemical complex chemical compound. and also identify chemical molecule in 3D. Similar function to all MS (depend on the analyzer and detector)


Is tof a membranophone?

No


What is the birth name of Tof Thissen?

Tof Thissen's birth name is Christoffel Paul Thissen.


When was Tof Thissen born?

Tof Thissen was born on May 19, 1957, in Roermond, Limburg, Netherlands.


Would the syllables in toffeemen be toff-ee-men or tof-fee-men?

It would be tof-fee-men.