Why bouin solution to fix testicular biopsy and not formalin?

Answer 1

Bouin's is generally used for testicular fixation because it preserves nuclei and chromosomes especially well, such as those you would want to observe during meiosis. Formalin is a more general fixative, used widely for other tissues when mitotic or meiotic cycles are not necessary to observe.

Answer 2

Bouin solution is preferred for fixing testicular biopsy samples because it provides better preservation of nuclear and cytoplasmic details in the tissue. Formalin can cause shrinkage and distortion of tissue structures, which may affect accurate histological interpretation. Bouin solution also helps maintain the morphology of delicate structures like spermatogenic cells.