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Most genetic disorders results from a mutation that changes the amino acid sequence in a?
Most genetic disorders result from a mutation that changes the amino acid sequence in a protein. This change can lead to altered protein function, which can affect normal cellular processes and result in disease.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
What is the main question to ask when considering the effect of a mutation?
The main question to consider when evaluating the effect of a mutation is how it alters the organism's phenotype or function. This involves assessing whether the mutation impacts protein structure or function, gene regulation, or any other biological processes that could affect the organism.
What is truncation mutation?
Truncation mutation is a type of mutation that results in the premature termination of the protein synthesis process. This leads to the production of a truncated or incomplete protein which may be nonfunctional. Truncation mutations can have serious consequences on the structure and function of the protein.
What happens when there is a mutation in a 5' UTR of mRNA?
If there is a mutation in the 5' UTR no change in the protein function and abundance will happen.
Does a DNA mutation always result in a change to the protein?
No, a DNA mutation does not always result in a change to the protein. Some mutations are silent and do not affect the protein's function.
How a mutation during replication can affect a protein that is synthesized?
A mutation during replication can lead to changes in the DNA sequence, which can consequently result in changes in the amino acid sequence of the corresponding protein. These changes can alter the protein's structure, function, or stability, ultimately affecting its overall biological activity. Depending on the nature and location of the mutation, the protein may exhibit loss of function, gain of function, or be unaffected.
How can a mutation in a gene affect the trait that an organism has?
A mutation in a gene can alter the functioning of the protein it codes for, leading to changes in the trait expressed by the organism. This can result in new traits, loss of function, or altered function of the protein, impacting the organism's phenotype.
How can a point mutation affect the protein created by the gene?
A point mutation can affect the protein created by a gene by changing a single nucleotide in the gene's DNA sequence. This change can alter the amino acid sequence of the protein, potentially leading to a different protein being produced. This can impact the protein's structure and function, which may result in a variety of effects on the organism.
Which sequence best represents the correct order of events involved for this mutation to affect the traits expressed by this cell?
Mutation occurs in the DNA of the cell. Mutation leads to changes in the sequence of amino acids in a protein. Altered protein function affects the traits expressed by the cell.
How is it possible for a point mutation to have no effect on the function of gene?
If the point mutation does not change the protein to be translated in the 3-letter sequence, then it will have no effect on the gene's function.
Most genetic disorders results from a mutation that changes the amino acid sequence in a?
Most genetic disorders result from a mutation that changes the amino acid sequence in a protein. This change can lead to altered protein function, which can affect normal cellular processes and result in disease.
What is a non polar mutation?
a mutation in a gene that does not affect the downstream genes in an operon. ie. a polar mutation is one that DOES affect the transcription or translation of genes in the same operon downstream of your gene of interest.
When a nitrogenous base is inserted or delete how does that affect the amino acid sequence?
The amino acid sequence is shifted, and this kind of mutation is called a frame shift mutation. All of the amino acid sequence after the mutation will be changed, which will cause a change in shape of the protein, which will then probably result in a nonfunctional protein, since the shape of a protein determines its function.
Why does an insertion mutation usually cause defects during protein synthesis than a point mutation?
Insertion mutations can affect many amino acids in the protein.An insertion mutation usually causes more defects during protein synthesis than point mutation because an insertion mutation will affect many amino acids in the protein.
A mutation in a gene may not affect an individual's phenotype because?
the mutation may occur in a non-coding region of the gene, resulting in no change to the protein produced. Additionally, the mutation may be silent, meaning it does not alter the amino acid sequence of the protein. In some cases, the organism may have redundant genes that compensate for the mutation, allowing it to function normally.
What is the main question to ask when considering the effect of a mutation?
The main question to consider when evaluating the effect of a mutation is how it alters the organism's phenotype or function. This involves assessing whether the mutation impacts protein structure or function, gene regulation, or any other biological processes that could affect the organism.
