answersLogoWhite

0

The N-terminal signal peptide is recognised by SRP (signal recognition particle). SRP directs the peptide to translocons on the membrane of the rough endoplasmic reticulum, usually during translation (co-translational). The translocon is responsible for the transport of the protein into the endoplasmic reticulum, from which it will either be secreted or sent to organelles such as the mitochondria, chloroplasts, endosome, lysomome and peroxisome. These organelles require that proteins go through the endoplasmic reticulum as the proteins are incorporated into the organelles through vesicular transport, as they do not have their own uptake methods.

Proteins destined for the nucleus are not sent through the endoplasmic reticulum, as the method of transport into the nucleus is not vesicular. Instead, the nucleus has its own pores capable of translocating proteins into the nucleus.

Small objects can pass through these nuclear pores by passive transport, but anything bigger than 40kDa requires a special mechanism. Proteins destined for the nucelus have a nuclear-localisation signal (NLS) instead of the N-terminal signal peptide. The NLS is a seven residue sequence of basic amino acids at the C-terminus.

User Avatar

Wiki User

16y ago

What else can I help you with?

Related Questions

Do proteins contain peptide bonds?

Yes, proteins are made up of amino acids linked together by peptide bonds.


What contains peptide bonds lipids proteins or nucleic acid?

Peptide bonds are primarily found in proteins. Lipids are made up of fatty acids and glycerol, while nucleic acids contain nucleotides.


What Biomolecule is formed by peptide bonds?

Proteins are formed by peptide bonds between amino acids.


What are bonds in proteins?

PEPTIDE


Which types of organic molecules have their monomers joined by a peptide bond?

Proteins have their monomers joined by peptide bonds. These monomers are amides. A number of amides are bond by peptide bonds to make proteins.


Do proteins contain uracils?

No proteins contain uracils as nucleotides are not part of the proteins. Uracils present in RNA(but not DNA). Uracil can pair with Adenine with a double hydrogen bond.


Which macromolecules has peptide bonds?

Peptide bonds are primarily found in proteins, which are polymers made up of amino acids. Peptide bonds form between the amino group of one amino acid and the carboxyl group of another amino acid during protein synthesis.


What type of bondings are present in proteins?

peptide bonds -CONH- the carboxylic group of one amino acid loses an OH group and the amino group of the other amino acid loses a H atom, eliminating a molecule of water for each peptide bond formed


What is linked by peptide bonds?

Amino acids are joined by peptide bonds to form proteins.


What enzymes is used to form proteins?

peptide bonds


What type of bond is specific to proteins?

Peptide bond


Are peptide bonds found in DNA?

Well... SORT of. Technically, the bases contain the NCO (amide) moiety that characterizes a peptide bond. However, they occur in heterocyclic rings, and it's stretching a point to call them "peptide bonds" since they're not linking two peptide residues. Also, they're in the cis-form, which is atypical of peptide bonds.