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Which part of nephron contains more and less amount of glucose and urea?
The proximal convoluted tubule of the nephron contains the highest concentration of glucose, as it is the primary site for glucose reabsorption from the filtrate back into the bloodstream. Conversely, the concentration of urea is higher in the distal convoluted tubule and collecting duct, as these segments are involved in the secretion and concentration of waste products, including urea. Thus, glucose is abundant in the proximal convoluted tubule, while urea is more concentrated in the latter parts of the nephron.
Why concentration of urea increased in PCT?
Urea is reabsorbed in the proximal convoluted tubule (PCT) of the nephron through both paracellular and transcellular pathways. The high water permeability and abundant transporters in the PCT facilitate the reabsorption of urea. If there is an increase in urea concentration in the filtrate, more urea will be reabsorbed passively and actively in the PCT to maintain urea balance in the body.
How are proximal convoluted tubule cells similar to enterocytes of the small intestine?
Both proximal convoluted tubule cells and enterocytes are involved in the absorption of substances: the proximal convoluted tubule cells reabsorb substances from the filtrate in the kidney, while enterocytes absorb nutrients from the food in the small intestine. Both cell types have microvilli to increase their surface area for absorption and are polarized to facilitate the transport of substances across their membranes.
What would happen to the intracellular and extracellular concentration of urea if the kidney stopped functioning?
If the kidney stopped functioning, the intracellular concentration of urea would increase due to impaired excretion. In contrast, the extracellular concentration of urea would also increase due to the diminished clearance of urea from the blood.
Why does the concentration of urea increase in the collecting duct?
The collecting duct is responsible for reabsorbing water in response to antidiuretic hormone (ADH). When water is reabsorbed, urea becomes more concentrated in the filtrate that remains in the collecting duct, leading to an increase in its concentration.
Why concentration of urea increased in PCT?
Urea is reabsorbed in the proximal convoluted tubule (PCT) of the nephron through both paracellular and transcellular pathways. The high water permeability and abundant transporters in the PCT facilitate the reabsorption of urea. If there is an increase in urea concentration in the filtrate, more urea will be reabsorbed passively and actively in the PCT to maintain urea balance in the body.
The sequence of structures that urea passes through in the nephron is?
Urea in the blood is filtered by the glomerulus into the Bowman's capsule, then it travels through the proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct. Urea can be reabsorbed and recycled back into the blood at various points along the nephron.
Which substances present in the glomerular filtrate but not normally in urine?
glucose and amino acids, because they are selectively reabsorbed in the proximal convoluted tubule.
How are proximal convoluted tubule cells similar to enterocytes of the small intestine?
Both proximal convoluted tubule cells and enterocytes are involved in the absorption of substances: the proximal convoluted tubule cells reabsorb substances from the filtrate in the kidney, while enterocytes absorb nutrients from the food in the small intestine. Both cell types have microvilli to increase their surface area for absorption and are polarized to facilitate the transport of substances across their membranes.
What would happen to the intracellular and extracellular concentration of urea if the kidney stopped functioning?
If the kidney stopped functioning, the intracellular concentration of urea would increase due to impaired excretion. In contrast, the extracellular concentration of urea would also increase due to the diminished clearance of urea from the blood.
Why does the concentration of urea increase in the collecting duct?
The collecting duct is responsible for reabsorbing water in response to antidiuretic hormone (ADH). When water is reabsorbed, urea becomes more concentrated in the filtrate that remains in the collecting duct, leading to an increase in its concentration.
How is urea reabsorbed?
40-50 % of filtered urea is reabsorbed through passive diffusion in the Proximal Convoluted Tubules. Loop of Henle, Distal Convoluted Tubules and Cortical Collecting Ducts are impermeable to urea. But secretion of urea happens in descending Loop of Henle (This helps to maintain the osmotic gradient in the medulla of the Kidney). There is also re-absorption of urea in the medullary collecting ducts.
What is reabsorbed by the proximal convoluted tubule cells?
The proximal convoluted tubule reabsorbs water, glucose, amino acids, ions (such as sodium and potassium), and other nutrients from the filtrate back into the bloodstream. It also reabsorbs a majority of the filtered bicarbonate, as well as small proteins.
Can you trace the path taken by a molecule of urea from the time it is produced in the liver to the time it leaves the body in the urine?
Renal artery à afferent arteriole à glomerulus à Bowman's capsule à proximal tubule à loop of Henle à distal tubule à collecting duct --> renal pelvis --> ureter --> bladder --> urethra
Nephron tube where nutrients are reabsorbed?
The Nephron is the functional unit of the Kidney which regulates blood contents NOT urine contents. It works by filtering out much of the contents of the blood from the Glomerulus into Bowmans Capsule. From here the a long tubule projects and is followed by a blood vessel (the Efferent Capillary) which reabsorbs much of the nutriens, what isn't reabsorbed goes into the Urine via a Collecting Duct. There are three parts to the nephron, the Proximal Convoluted Tubule, the Loop of Henle and the Distal Convoluted Tubule. The loop of Henle is mostly involved in the reabsorbtion of water with the use of salts. The majority of nutrients reabsorbtion takes place is the proximal convoluted tubule. It should be noted that although the nephron is very efficient (it reabsorbs 90% of the water if need be) it also reabsorbs about 50% of the urea so it is incorrect to think that it all goes straight into the urine. In short, to answer you question, most nutrients are reabsorbed in the Proximal Convoluted Tubule.
Why is it important that the concentration of urea is kept very low in the dialysis fluid?
the concentration of urea should be kept low in the dialysis fluid because urea is harmful for our body if it is not removed.
How urea is produced and trace the part taken by a molecule of urea by the time it is produced in the liver to the time it leaves the body as urine?
Urea is made from ammonia filtered out of the blood by the nephrons in the kidney. As ammonia is a highly toxic substance to humans, and humans have moderate water supplies, it undergoes multiple chemical reactions to convert from ammonia to urea which is diluted to urine and excreted out of the urethra. from the blood, into the kidneys, into the NEPHRONS: okay so the blood flows through capillaries called the GLOMERIUS (spelling...?) where blood pressure squeezes it out into the the bowl the glomerius is in called BOWMAN's CAPSULE. through the proximal tubule, loop of henle, distal tubule, collecting duct into the RENAL PELVIS thorough the URETER to the BLADDER down through the URETHRA
