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The ventricular action potential has a long refractory period so that the mechanical response of the ventricle will be discrete; one coordinated mechanical response per electrical activation sequence. Otherwise, with additional electrical stimuli, the mechanical responses would summate producing a prolonged contraction.

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2 Define refractory period and differentiate between absolute and relative refractory periods?

refractory period is the interval between action potential , the absolute refractory period is the period in which second action potential can not be initiated but in relative refractory period the second action potential can be initiated by the more strong stimulus.


What is the relationship between the absolute and relative refractory periods during the action potential process?

During the action potential process, the absolute refractory period is when the neuron cannot respond to any stimulus, while the relative refractory period is when it can respond to a stronger stimulus. The absolute refractory period comes before the relative refractory period in the action potential process.


What dysrhythmia does amiodarone treat?

Amiodarone is primarily used to treat ventricular dysrhythmias, particularly ventricular tachycardia (VT) and ventricular fibrillation (VF). It is also effective in managing atrial fibrillation and atrial flutter, especially in patients with heart failure or structural heart disease. The drug works by prolonging the action potential and refractory period in cardiac tissues, helping to restore normal rhythm.


What is the cause of the relative refractory period?

The Refractory period is when a second action potential is possible, but unlikely; second action potential only if the stimulus is sufficiently strong. The refractory period helps to prevent backflow of Sodium.


What is The time an action potential begins until the resting potential has stabilized is?

1/2500 sec is the absolute refractory period.


A period after an initial stimulus when a neuron is not sensitive to another stimulus is the?

refractory period. This is a brief time after a neuron has fired an action potential, during which it cannot generate another action potential in response to a new stimulus. This period is crucial for maintaining the directionality of signal transmission in the nervous system.


What happens during the refractory period?

The voltage-gated Na+ channels get deactivated, thus the sodium ions cannot diffuse into the cell and cause depolarisation and this also provides time for the membrane to prepare for its second action potential.


Define the period of repolarization when only a strong stimulus will elicit an action potential?

The period of relative refractory period is the time after an action potential during which a strong stimulus is required to generate a new action potential. This is because the membrane potential is hyperpolarized, making it more difficult to reach the threshold for firing another action potential.


What is the absolute refractory period?

Absolute Refractory Period:It is the interval during which a second action potential absolutely cannot be initiated, no matter how large a stimulus is applied.ORAfter repolarization there is a period during which a second action potential cannot be initiated, no matter how large a stimulus current is applied to the neuron. This is called the absolute refractory period, and it is followed by a relative refractory period, during which another action potential can be generated


During which period can a second action potential be initiated by a larger than normal stimulus?

The period following the absolute refractory period is where a second action potential can be initiated by a larger than normal stimulus. This phase is known as the relative refractory period.


When do you use relative refractory period?

The relative refractory period is the time during which the generation of an action potential is impossible no matter the strength of the stimulus


Absolute refractory period relative refractory period?

In absolute refractory period, none of channels are reconfigured, so that second active potential cannot be generated no matter how large the stimulus current is applied to the neuron. In contrast, in relative refractory period, some but not all of channels are reconfigured, another action potential can be generated but only by a greater stimulus current thatn that originally needed.