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What happens if red blood cells don't work properly?
Sickle cell anaemia is the product of long term evolutionary pressures due to endemic malaria. The malaria parasite cannot survive in sickle cells, which is why the disease is so common among people who share African genes (where malaria is prevalent). The disease is inherited, but partially recessive, giving people that are heterozygous for the trait a huge advantage, as complications are less likely (there are many 'normal' red blood cells to make up for the anaemia that results from sickled cells), but they still have the protection against malaria. The cause is a missense point mutation in the beta hemoglobin gene, which causes hemoglobin in red blood cells to aggregate under low oxygen conditions. This aggregation leads to the red blood cell becoming rigid and changing in shape to the characterisitic sickle shape that the disease takes its name from. Although the disease succesfully protects against malaria, which has kept it endemic despite its high mortality rate, the rigid sickle shape cells can get caught up in blood vessels much more easily than normal cells, vastly increasing the risk and frequency of blood clots. This is a particular problem for people who are homozygous for sickle cell anaemia, since all of their red blood cells have this problem. Destruction of sickle cells by the body takes place in the pancreas, since the strangely shaped cells are not recognised as being 'real' red blood cells, which causes the anaemia.
What is the promlem of sickle-cell anemia?
sickle cell trait is a gene inherited from one parent which gives partial immunity to malaria and but is unlikely to develop into sickle cell anemia.The same gene inherited from BOTH parents causes Sickle-cell anemia, a blood disorder in which the body produces abnormal type of hemoglobin in red blood cells and can be deadly.
Among living things the most common among the polysaccharide structural carbohydrates is?
Among living things, the most common among the polysaccharide structural carbohydrates is cellulose. Cellulose is the monosaccharide that composes the hard bodies of crabs and insects.
Is there any evidence that the traits shared by most of the population is not controlled by a dominant allele explain?
The presence of a dominant allele is not always required to explain common traits in a population. Polygenic inheritance, where multiple genes contribute to a trait, can lead to common traits without a dominant allele. Additionally, environmental factors can also play a significant role in shaping common traits among a population.
What features were common among artworks in the international Gothic style?
it tended to be portable
What is common among haemophilia down's syndrome and sickle cell anaemia?
all of them are caused by genetic mutations
Which race is more commonly inherited with sickle cell disease?
Sickle cell disease is more common among blacks than among people of other races.
What kind of a disease is sickle cell anaemia?
It's not a disease, it is a hereditary disorder. Basically it is a problem with irregular red blood cell shape, which can cause pain in the arteries and veins, among other things.
What are the different types of sickle cell disease and how do they differ from each other?
There are several types of sickle cell disease, including sickle cell anemia, sickle beta thalassemia, and sickle cell-hemoglobin C disease. These types differ based on the specific genetic mutations that affect the hemoglobin protein in red blood cells. Sickle cell anemia is the most common and severe form, where individuals have two copies of the sickle cell gene. Sickle beta thalassemia and sickle cell-hemoglobin C disease are milder forms that result from different combinations of genetic mutations. Symptoms and complications can vary among the different types of sickle cell disease.
Why do sickle cell anemia cause so many problems?
A sickle cell is a malformed red blood cell. It is caused by a mutated gene inherited from one or both parents. If inherited from both parents the red cells are very malformed, causing sickle-cell anaemia. This is a serious illness, causing weakness and shortness of breath and often leading to an early death.Mutations like this are usually steadily removed from the gene pool because those with it tend to have fewer children. The sickle-cell gene remains in the gene pool because those who get it from only one parent have a slightly deformed red-cell. This causes only limited problems for the bearer, and has one large advantage - it makes the red-cell taste nasty to the malaria parasite. In other words, it protects against malaria which is otherwise often fatal.In areas where malaria is endemic it is common to find the sickle cell gene in about 15% of the population. When Africans came to the USA as slaves the gene came with them. However, malaria has never been common in the US, and the percentage of sickle-cell gene in black Americans has decreased steadily.
What type of anemia is a genetic disease commonly found among of Africa descent?
Sickle cell anemia
What confederation among tribes fighting in the northeast?
Britsh
What are the tribes of Iraq?
There are hundreds of tribes in Iraq (especially among the Arab population as Kurds do not typically have tribes). Please see the Related Link below for a sizable list of Iraq's tribes.
What type of anemia is a genetic disease commonly found among people of African descent?
Sickle cell anemia.
What type of anemia is a genetic disease typically found among people of African descent?
the disease is sickle cell
What happens if red blood cells don't work properly?
Sickle cell anaemia is the product of long term evolutionary pressures due to endemic malaria. The malaria parasite cannot survive in sickle cells, which is why the disease is so common among people who share African genes (where malaria is prevalent). The disease is inherited, but partially recessive, giving people that are heterozygous for the trait a huge advantage, as complications are less likely (there are many 'normal' red blood cells to make up for the anaemia that results from sickled cells), but they still have the protection against malaria. The cause is a missense point mutation in the beta hemoglobin gene, which causes hemoglobin in red blood cells to aggregate under low oxygen conditions. This aggregation leads to the red blood cell becoming rigid and changing in shape to the characterisitic sickle shape that the disease takes its name from. Although the disease succesfully protects against malaria, which has kept it endemic despite its high mortality rate, the rigid sickle shape cells can get caught up in blood vessels much more easily than normal cells, vastly increasing the risk and frequency of blood clots. This is a particular problem for people who are homozygous for sickle cell anaemia, since all of their red blood cells have this problem. Destruction of sickle cells by the body takes place in the pancreas, since the strangely shaped cells are not recognised as being 'real' red blood cells, which causes the anaemia.
America's richest Indian tribes?
The Shakopee Mdewakanton is America's richest Indian tribe. Other tribes that are among the richest include the Puyallup, and the Nisqually tribes.
