"De que" would be "Of what" in English.
Of which or of what.
hablando
it means so what do you want to talk about (de que = about what, quieres = you want, hablar = to talk) :-)
It means, "What is there [that's] good?"
how was your weekend?
Of which or of what.
'¿De que te ries?' means 'What are you laughing at?' or 'What's so funny?'
hablando
But from what city
What are you talking about?
"de lo que" would vary depending on the context it is used in - but the direct translation would be "than".
Qu'est-ce que tu penses de l'école? in French is "What do you think about the school?" in English.
"Nada de qué" in Spanish means "nothing of what" in English. This phrase is often used to express confusion or a lack of understanding in response to someone's statement or question.
how was your weekend?
What kind of exercises do you do?
It means, "What is there [that's] good?"
it means so what do you want to talk about (de que = about what, quieres = you want, hablar = to talk) :-)