Raccoons and large possums are the largest things.
Rodents and small game.
A .22 rifle can potentially kill animals such as deer or feral hogs with well-placed shots. It is important to ensure responsible and ethical hunting practices when using a firearm for hunting purposes.
Animals as big as the Grizzly Bear have been shot with a .22 rifle. I do not recommend it, since the bear is likely to eat you. .22 rimfire should be limited to small game in the rabbit-size category.
You use a 22. rifle
None
Biggest threat is a landowner with a 22 rifle or 12ga shotgun.
Definitely Yes.
Yes. But I suggest using hunting pellets.
Definitely Yes it can.
Many would say the 22 Long Rifle.
That's a very vague question. If you mean a .22 caliber rifle, the techincal answer is, almost anything. It's possible for a .22 to kill almost any animal, it just isn't extremely likely in some cases.
With a properly placed shot, anything from a .22 long rifle on up.