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Infants are at risk for drug toxicity due to their immature liver and kidneys, which are not fully developed and can impair drug metabolism and excretion. Additionally, their body composition differs from adults, with a higher percentage of water and lower fat content, affecting drug distribution and concentration. Infants also have different enzyme activity levels, which can alter drug efficacy and safety. Lastly, dosing is often based on weight, and errors in calculation or administration can lead to overdosing or underdosing.

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5mo ago

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