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Outbreaks of plague, which would be pneumonic plague rather than Bubonic Plague (sometimes known as the Black Death), within the City of London, caused the theatres close to the City to be closed down, including the ones Shakespeare was working at. Henslowe's Diary suggests that in 1594, towards the end of a particularly nasty plague outbreak, the Lord Chamberlain's Men (which would have included Shakespeare) were performing at Newington Butts theatre south of London and out of the plague area.

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