Methyl salicylate, C6H4(OH)COOCH3, is the methyl ester of salicylic acid, and the principal constituent of oil of wintergreen and oil of sweet birch, existing in the former to the extent of about 99 per cent., and in the latter to about 99.8 per cent. It is official in the U.S.P. Much of the oil of wintergreen of commerce, however, is the synthetic methyl salicylate, which is practically identical with the natural products. It may be prepared by dissolving 14 of salicylic acid in 60 of methyl alcohol, then gradually adding 30 of sulphuric acid, warming for about twenty-four hours, and distilling in a current of steam. The distillate is subsequently washed and separated. Methyl salicylate occurs as a colourless, or pale yellow, oily liquid with the strong, characteristic odour and aromatic, sweetish taste of wintergreen. Specific gravity, 1.183 to 1.188; boiling-point, 219° to 221°. Optically inactive. The aqueous solution is neutral or slightly acid to litmus, and yields with a trace of ferric chloride an intense violet colouration. It should form a perfectly clear solution with 5 parts of alcohol (70 per cent.) at 20°. On distillation in a flask it should yield no fraction containing alcohol or chloroform. On adding 10 mils of solution of potassium hydroxide (5 per cent.) to 1 mil of the methyl salicylate in a large test-tube, and shaking, a clear, colourless, or faintly yellow solution should result, without separation of oily drops on the surface or at the bottom of the liquid (absence of volatile oils or of petroleum). The alkaline liquid, on dilution with three volumes of water and the addition of slight excess of hydrochloric acid, yields a white crystalline precipitate of salicylic acid, which, on washing and drying, should respond to the tests for the purified substance (absence of methyl benzoate, etc.). Slightly soluble in water, soluble in all proportions of alcohol, ether, chloroform, glacial acetic acid, or carbon bisulphide. Action and Uses.-Methyl salicylate is rapidly absorbed when rubbed on the skin, and this property allows the concentration of its action upon rheumatic and stiff joints and in lumbago; it may also be applied to the forearm or any convenient surface for the general action of the salicylates in acute and chronic rheumatism, pharyngitis and chorea, etc. (see Sodii Salicylas). In acute lumbago, massage with methyl salicylate acts almost immediately; and it has been shown that, in the most inveterate cases of stiff back, with the presence of rheumatic nodules, such massage, applied at intervals for a month or two if necessary, will generally remove the condition. The pure substance may be painted on the skin and covered with oiled silk or gutta percha tissue, or it may be mixed with an equal quantity of olive oil and applied with gentle friction or on lint. Methyl salicylate should be used for application to the skin rather than natural oil of wintergreen, as the latter frequently causes irritation and may give rise to a rubeoliform eruption. It is recommended for local application in orchitis and mumps. An ointment of methyl salicylate with hydrous wool fat (1 in 8) is prepared for use in rheumatism and neuralgia, menthol (1 in 16) being sometimes added. Methyl salicylate is administered in acute and chronic rheumatism enclosed in a Gelatin capsule (5 or 10 minims in each). It may be emulsified with mucilage of gum acacia and given in mixture form, but its taste is pungent and objectionable. It is used as a flavouring agent, and as an antiseptic in mouth washes, tooth pastes, and powders. Mesotan, salicylic-methoxy-methylester, is an odourless liquid, used as a substitute for methyl salicylate. It is soluble in alcohol and decomposed by water. Mixed with an equal quantity of olive oil, it is known as Mesotanol and is applied for rheumatism. Spirosal, the mono-glycol ester of salicylic acid, is a colourless and odourless liquid soluble in alcohol or olive oil. It is applied in lumbago and rheumatism diluted with 3 parts of alcohol or olive oil.
Yes, each sample of a substance occupies space due to its physical dimensions and the volume it occupies in a container. The amount of space a sample occupies is known as its volume.
The half life of a sample is the time in which the sample decays to half its mass. It depends only on the material(to be exact on its decay constant) and not the quantity .Hence, the half life of the sample remains the same.
oxygen
A spectrophotometer measures the intensity of light at different wavelengths that pass through a sample. By comparing the amount of light absorbed or transmitted by the sample at different wavelengths to a reference, the spectrophotometer can determine the concentration of a substance in the sample.
Spectrometers work by measuring the interaction between light and a substance. When light is passed through a sample, the substance absorbs certain wavelengths of light based on its composition. By analyzing the absorbed wavelengths, spectrometers can determine the elements or molecules present in the sample.
copper oxide...
Methylsalicylate is called oil of wintergreen because it is primarily found in the wintergreen plant (Gaultheria procumbens). The compound gives off a characteristic aroma similar to that of wintergreen berries, hence the name.
what is a substance containing all of the same type of atom
Density of a substance = (mass of a sample of the substance) divided by (volume of the same sample)
it has no effect. density of a substance is the same no matter the size or shape of the sample.
It is important to perform tests on a control urine sample not containing any chemical substances, a test result on a known quality can assist you in finding the unknown qualities of a urinary sample containing chemical substances. It also can validate any positive results you get with your test sample.
To find the number of moles in a sample, divide the sample's mass by the substance's atomic mass unit (amu). For a substance with an amu of 12, the number of moles in the sample can be calculated by dividing the sample's mass by 12.
An effervescent substance is a substance that is either containing bubbles or producing bubbles.
Sample X is likely a solution containing a soluble substance (B) and an insoluble substance (Y). When passed through the filter paper, the insoluble substance Y is caught while the soluble substance dissolves in liquid Z, which passes through. Upon vaporizing liquid Z, the soluble substance B remains as a white residue. Thus, sample X is a mixture of an insoluble solid (Y) and a soluble compound (B).
Density of a substance = (mass of a sample of it)/(volume of the same sample)
To determine the number of lb-moles in a sample, divide the weight of the sample in pounds by the molecular weight of the substance. This will give you the number of lb-moles present in the sample.
A very large, specific number of items