Take the Downtown A-C-E (the blue line) from 34th Street-Penn Station to West 4th Street (doesn't matter which you take, the A, C or E, since all three stop at West 4th). Transfer at West 4th Street to the Uptown F train (of the B-D-F-M, the orange line) to 21st Street-Queensbridge in Queens (Long Island City is in Queens). This is the first stop the F train makes in Queens. It's the next stop after Roosevelt Island.
The 21st Street-Queensbridge Station is at or near the corner of 41st Avenue and 21st Street. Walk one block north on 21st Street to 40th Avenue. Cross 40th Avenue, and continue up 21st Street about half a block to the Best Western at 39-34 21st Street between 40th and 39th Avenues.
Buchanan Street subway station was created in 1896.
Merkland Street subway station was created in 1896.
Merkland Street subway station ended in 1977.
West Street subway station was created in 1896.
Bridge Street subway station was created in 1896.
If you are taking Bloor-Danforth subway line, then nearest subway station is Bay station, which is 1.8km north from 610 Bay Street. On Yonge-Unitversity-Spadina, Dundas station is closest to 610 bay street (300 m east)
Take the subway eastbound from the Amtrak station (30th Street Station) to 11th Street.
To get from Penn Station to Worth Street, you can take the 1 subway line. Board the 1 train at 34th Street-Penn Station and travel downtown. Get off at the Chambers Street station, which is close to Worth Street. Alternatively, you could take the A or C train from 34th Street-Penn Station to Chambers Street for a similar route.
Walk two blocks to 13th & Market Streets. Take the subway from 13th Street to 30th Street Station.
The nearest subway station to 199 Lafayette Street is the Bleecker Street station, which serves the B, D, F, and M trains. Another close option is the Spring Street station, which is served by the C and E trains. Both stations are within a short walking distance from the address.
To get to the Hayden Planetarium from Penn Station, take the A, C, or E subway line from 34th Street-Penn Station. Transfer at 42nd Street-Port Authority Bus Terminal to the 1 subway line, then travel uptown to 79th Street. From there, it's a short walk to the American Museum of Natural History, where the Hayden Planetarium is located.
To travel from Penn Station to 851 Grand Concourse in the Bronx, take the 2 subway line from 34th Street-Penn Station station towards Wakefield-241st Street. Transfer at the 149th Street-Grand Concourse station to the 4 or 5 line, and then continue to the 167th Street station. From there, it's a short walk to your destination at 851 Grand Concourse.