Is Judaism the only religion that lost its holy land and has regained it?

Answer 1

Yes and No.

Shenists Chinese people lost their holy lands to Yassai Mongol control in the mid-1200s and the Hindus of India lost their holy lands to the Muslim Mughal Empire. Both of these peoples eventually regained political contol over their holy lands. Unlike the Jews, however, they still lived on their lands in relative security during the foreign occupations described. The Jews were unique in that they returned to their holy land and gave it independence after a long period of minimal presence and non-control.

It is important that we don't forget the many Native American tribes. The Lakota Sioux were largely driven out of the Black Hills of South Dakota. The Nez Pierce where mercilessly chased across half the continent and escaped to Canada. The Cherokee lost most of their lands and were left with a small patch in North Carolina, and later a scrubby plot in central Oklahoma. The Seminole were dragged out of Florida, but some were later repatriated.