Who was the major prophet who spent his entire life outside israel and judah?
Assuming that you are talking about Juudaism, there are a few:
Moses, Ezekiel, and Daniel, among others.
Of course, with the exception of certain sects of Christianity,
the overwhelming majority of non-Jewish prophets spent their entire
lives outside of Israel and Judah, including: Mohammed, Buddha, Lao
Tzu, Joseph Smith, etc.