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Hardening of the arteries due to cholesterol plaques is called atherosclerosis or arteriosclerosis. The term Atherosclerosis literally means "hardening from atheroma". In a healthy person, the artiers have walls that are muscular, smooth and elastic enough to allow for variations in blood pressure, which allows the blood to pass through freely.

In people who don't watch their diet (especially their fat intake), fatty streaks appear on the inner walls of arteries. As the fatty streaks grow, it causes further damage to the arteries, and the fatty streaks harden. This results in erosion of the arterial walls, diminishes the elasticity of the artery, and narrows the passageway which interferes with the flow of blood. The fatty tissue is known as atheroma.

This process is a major factor in Heart disease, stroke and high blood pressure, among other health problems, but it can be controlled, and even prevented by maintaining a healthy, low fat diet, and exercising on a regular basis.
Arteriosclerosis is the same thing as hardening of the artery. Arteriosclerosis is the medical word.

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