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Amoebas can have several negative effects, particularly when they are pathogenic. For instance, the species Entamoeba histolytica can cause amoebic dysentery, leading to severe diarrhea, abdominal pain, and dehydration. Additionally, some free-living amoebas, like Naegleria fowleri, can cause fatal brain infections in humans. Their presence in contaminated water sources can pose significant health risks, particularly in immunocompromised individuals.

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