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That is hard to say because the frequency of Down syndrome if a function of maternal age so it is not fixed. A mom between 20 and 24 years old has a 1/ 1400 risk of having a child with Down syndrome. A mom who is 45 or older has a 1/25 risk.

Overall, it is fair to say Down syndrome is one of the most common and best known genetic disease.

Other genetic disease such as Cystic Fibrosis, hemochromatosis are also common.

The frequency of all these things varies in different populations as well as age.

So the question is quite hard to answer without isolating a specific population.

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15y ago

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