It is not actually known exactly how many people have died from cholera, which is an acute intestinal infection caused by ingestion of contaminated water or food, but it is safe to say that the most died before water treatment plants and other facilities were created. Many died from cholera while on the open prairie in the Wild West.
In the Victorian era, about 7000 people died from cholera.
Cholera is caused by a bacteria that attacks the lining of the colon. There are really two main reasons so many people die from this disease. One is that the onset of the disease is extremely fast, so there isn't always adequate time to obtain treatment. Death can occur in one or two days. The second is that the disease frequently occurs after flooding or other natural disasters in impoverished areas. This means that medication (antibiotics), clinics, doctors are frequently not available or accessable.
Cholera comes in epidemic. Patients come with acute onset vomiting and profuse diarrhoea. There is no fever and pain in abdomen. Typically, there is 'rice water' stool. The diagnosis is confirmed by culture of vibrio cholerae bacteria from the stool sample. In your clinical practice you get isolated patients of watery diarrhoea without pain in abdomen and no fever. You make a diagnosis of cholera like syndrome. You give tablet furazolidone 100 mg stat, fallowed by two tablet three times a day. Many times the loose motion stops abruptly, with first dose only. This gives you the presumptive diagnosis of cholera in a given case. This is fairly common occurrence in your clinical practice.
What was the cause of the cholera outbreak in London in 1854?
Dundee in the 19th century would have been smelly and crowded, with noisy markets and narrow cobbled streets traversed by horses and carts and littered with deposits of horse dung. Street-side butchers and fish vendors like those found at Butchers Row and Fish Street would often toss innards and unwanted flesh into street gutters, and householders threw refuse from tenement windows into the streets below. In the early 1800s, toilets were outdoors and shared by many families living in the same tenement block, and few public washing facilities were available for bathing. Dung heaps were often situated too close to public wells and triggered complaints from citizens about their drinking water being contaminated with faeces.
Why does Cholera kill its victims so quickly?
The bacteria Vibrio Cholerae causes extreme, violent diarreah which rapidly dehydrates the host, leading to a quick death
Cholera was a deadly disease that appeared in 1861 during the Civil War. Many soldiers and other citizens died immediately overnight if they had the disease called Cholera because it was so deadly. There was no type of medicine or cure to help save their dangered lives. Poor soldiers' and citizens' lives were lost because of Cholera.
Why profuse diarrhea related to cholera?
The Cholera toxin is an enzyme that chemically modifies proteins in your body that involve regulating salt and water secretion. The modified proteins remain stuck in its active form, continuously secreting large amounts of salts int the intestines with water following (dude to osmosis). The excessive amount of water causes diarrhea and can kill a person from loss of water and salt.
Why is there no vaccine for cholera?
As of June 2014, there are two types of vaccine for cholera. The first is Dukoral which is available in more than 60 countries worldwide and the second is ShanChol, which is available in India but is pending WHO approval.
Is vibrio cholerae a bacterium?
Vibrio choleae is a bacterium. It is gram negative, curved rod shaped and has a single flagella. There are numerous strains some of which are responsible for causing the disease cholera.
Yes, Cholera can be treated and cured. However there is no vaccination, so even if you are cured, you could catch it again.
Cholera is treated by replacing fluids and electrolytes in your body which are lost by diarrhoea.
See the related question below for more information.
What is the meaning of the cholera fever?
The word itself means: a gutter.
Cholera is a severe bacterial infection caused by the bacterium Vibrio cholerae, which primarily affects the small intestine and the main symptoms include production of profuse watery diarrhea and vomiting. Transmission is primarily by the acquisition of the pathogen through contaminated drinking water or infected food. The severity of the diarrhea and associated vomiting can lead to rapid dehydration (hypohydration) and electrolyte loss. If these are not replaced then death may follow.
Aside from continuing to be a major cause of death in the world, study of cholera has been used as an example of early epidemiology. Study of the V. cholerae bacterium has also shed light on many of the mechanisms used by bacteria to infect and survive in their hosts.
What countries still get infected with cholera?
cholera affects the countries which have poverty & cannot afford clean water.
ie India Brazil and Peru.
You can cure the cholera by heavy infusion of the intravenous fluids. You may have to put two infusion lines with large bore needle or intracath or vasofix. You have to give ringer lactate solution with added potassium chloride in the bottle. Direct potassium chloride will kill the patient in no time. Give the fluid ruthlessly. You may give four liters of fluid in first hour only. You have to keep the heart rate to about 100 per minute and systolic blood pressure at about 100 mm of Hg. The fluid should be warmed to body temperature. Total non-touch technique has to be used to maintain the aseptic transfusion unit. Patient will not complain of thirst due to loss of isotonic fluid. But then his routine need of water is to be satisfied by giving him 10 % dextrose solution two to three litres per day. You can give him one ampule of multivitamin per day in dextrose solution. Once vomiting is controlled, you can give him oral re-hydration solution to save I. V. fluids. With proper and confident treatment the patient will not die. You may have to give up to 30 litres of fluids in say two days, apart from oral re-hydration fluids. You can give him injection oxytetracyline (Teramycin) twice a day for two to three days.
Is cholera and diphtheria the same?
No. They are different diseases. In diphtheria you get a patch on throat. That was a serious condition. It is almost eliminated by universal vaccinaton. In cholera you get severe vomiting and loose motion.
How long does it take to get the symptoms of cholera?
Since Cholera is a disease that can cause severe dehydration, this can create issue with the kidney. In severe cases kidney failure occurs and sometimes this is not reversible. This is the only known long term effect of Cholera.
Is Vibrio cholerae helpful or harmful and why?
Cholera is harmful.
"Cholera is an infection of the small intestine that causes a large amount of watery diarrhea."
Potentially anywhere, you only need to have a dirty water (or food) supply that has the bacterium of cholera. Countries that you are likely to catch it in are probably third world countries with bad hygiene that could cause sewage to leak into water supplies.
Is cholera a virus or a bacteria disease?
Cholera is a diarrheal illness caused by a toxin produced by the bacterium Vibrio cholerae. The toxin causes massive amounts of water to be excreted into the lumen of the bowel, thus producing copious watery diarrhea. The danger is not from the diarrhea, but instead from the dehydration it produces. Children and the elderly are especially at risk.
How did dr john snow stop the disease cholera?
Name of Dr. John snow is permanently associated with the cholera. He was a physician in London. Dr. John Snow prepared the dot map of the cholera patients. He could locate the origin of cholera on Broad street (now Broadwick street) of Soho district of London. Almost all the patients had consumed water from one particular pump. Some monks from the area were not affected by cholera. But then, they did not used the water for drinking. But instead they used to consume beer to quench the thirst. The theory was not accepted immediately. But then, you can not hide the truth for long. Just like that, you can not hide the sun with your hands.
What is cholera and how do you get it?
The vector (the way the illness is spread) is mainly through contaminated water. There are most likely other ways you can catch the bacteria, but contaminated water is where the index case starts.
What does the disease cholera infect?
Cholera is a disease that occurs through drinking or eating food or liquids contaminated with Vibrio cholerae . It affects animals and humans. Famous people such as Alexander Dumas(French author), Pyotr Ilyich Tchaikovsky(Russian composer) and Adam Mickiewicz(Polish author) died of this disease although historians argue that Tchaikovsky infected himself purposely.