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Pseudoephedrine and Phenylephrine (Sudafed)

Pseudoephedrine is a stimulant medication used to treat the symptoms of the common cold, sinusitis and nasal congestion. While pseudoephedrine appears in small doses in many popular, over-the-counter decongestants, the product is heavily regulated. Pseudoephedrine's chemical structure is very similar to that of amphetamine, making it a key component in some illegal drugs. Due to the tight regulations, Phenylephrine is often sold as an over the counter substitute.

410 Questions

Can Pseudoephedrine give false positive for amphetamines?

Yes. All variations of methamphetamine, amphetamine, methcathinone and ephedrine have very similar molecular structures, and they all break down to the same compound in your body. In fact, ephedrine is a necessary precursor in synthesizing the other three drugs.

Urine tests, especially portable on-the-spot ones, are designed to detect this compound that these drugs break down into, not the drugs themselves, so whether you are on methamphetamine, amphetamine, methcathinone, or ephedrine or even pseudo ephedrine, you can test positive for amphetamines.

If you do test positive and you know you were only on ephedrine or pseudoephedrine, you can request a re-test that involves a proper lab using blood or hair samples

Can you take Sudafed with buspirone?

In my professional opinion Buspirone is useless as an anti-anxiety drug. Sudafed can cause anxiety. I do not see why one would want to, but there is no problem doing it.

Can you take paracetamol and pseudoephedrine together?

Yes, paracetamol is the European generic name for acetamimophen, and when taken with pseudoephedrine would form the U.S. equivalent of Tylenol-D, a combination pain reliever and decongestant.

Can you give your dog Pseudoephedrine?

Overview

* Pseudoephedrine is a central nervous system stimulant classified as a sympathomimetic alkaloid agent and is similar to ephedrine.

* Pseudoephedrine causes the release of the sympathetic nervous system chemical norepinephrine. The involuntary nervous system is divided into the sympathetic (flight or fight response) and parasympathetic branches. In general, these two systems oppose each other.

* When stimulated, the sympathetic system increases heart rate, blood pressure and cardiac activity. It also dilates the bronchial tree and contracts certain smooth muscles.

* When compared to ephedrine, pseudoephedrine has only 25 percent the effect on blood pressure and 50 percent the effect on dilating airways.

* This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug.

* Pseudoephedrine is available without a prescription but should not be administered unless under the supervision and guidance of a veterinarian.

Brand Names and Other Names

* Pseudopseudoephedrine is available in many different over-the-counter (OTC) products. It is also commonly available in combination with other drugs, such as decongestants and cold remedies.

* This drug is registered for use in humans only.

* Human formulations: Pseudoephedrine is supplied by numerous drug companies with a variety of trade names and various generic formulations.

* Veterinary formulations: None

Uses of Pseudoephedrine

* For its bronchodilator activity, pseudoephedrine has been used in the treatment of respiratory conditions like bronchitis and nasal congestion in dogs; however, other drugs such as theophylline and terbutaline are more often prescribed.

Precautions and Side Effects

* While generally safe and effective when prescribed by a veterinarian, pseudoephedrine can cause side effects in some animals.

* Pseudoephedrine should not be used in animals with known hypersensitivity or allergy to the drug.

* Little information is available on the safety of pseudoephedrine use in cats. For this reason, use in cats should be avoided.

* Pseudoephedrine may interact with other medications. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with pseudoephedrine.

* Common side effects associated with pseudoephedrine include nausea, loss of appetite, vomiting, changes in behavior (agitation, restlessness), increased heart rate, muscle tremors and seizures.

* Pseudoephedrine should be avoided in animals with hyperthyroidism, glaucoma, diabetes mellitus, hypertension and disorders of the cardiovascular system.

How Pseudoephedrine Is Supplied

* Pseudoephedrine is available in 30 mg and 60 mg tablets. It is also available in 120 mg capsules.

* Pseudoephedrine syrup is available in a 6 mg/ml concentration.

Dosing Information

* Medication should never be administered without first consulting your veterinarian.

* Pseudoephedrine is dosed in dogs at 0.1 to 0.2 mg per pound (0.2 to 0.4 mg/kg) or 15 to 60 mg per dog by mouth every 8 to 12 hours.

* The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects. Be certain to complete the prescription unless specifically directed by your veterinarian. Even if your pet feels better, the entire treatment plan should be completed to prevent relapse or prevent the development of resistance. The Down Side: * "Pseudoephedrine has a very narrow margin of safety in dogs, cats, and other animals," says Dr. Steve Hansen, senior vice president of the ASPCA Animal Poison Control Center, which has issued the warning. * Pseudoephedrine is found in certain cold, allergy, and sinus medications used in humans. As little as one tablet containing 30 mg of pseudoephedrine can induce clinical signs in a 20-pound dog, including nervousness, hyperactivity, and other behavioral changes; panting; fast heart rate; and high blood pressure. A dose as small as three 30-mg tablets in the same size dog can be lethal. * "Clinical effects can sometimes be seen as quickly as within 30 minutes after ingestion," Dr. Hansen says. "Therefore, it is critical that veterinary treatment is sought quickly when an ingestion occurs." * As with most medications, animal exposures to pseudoephedrine products usually are accidental, such as a pet chewing into a medication bottle or ingesting pills left unattended. Others may occur as a result of pet owners inappropriately medicating their pets. * Pseudoephedrine and other medications should be kept out of the reach of animals, preferably in a secure cabinet above the counter, according to the poison control center. "It is very important for owners to understand that even childproof containers are not effective in preventing accidental drug exposures in pets, as dogs and other animals can easily chew open a bottle or vial," Dr. Hansen says. * Individuals who suspect a pet may have ingested a pseudoephedrine-containing product or other drug should contact their local veterinarian or the ASPCA Animal Poison Control Center at (888) 426-4435 for immediate assistance.

Can phenylephrine test positive for opiates in a urine test?

Yes. Codine is an ingredient in both phenylephrine and oxycodone. Oxycodone is an opiate.

How long does it take Sudafed to work?

Depends on the medication and how it's administered. Inhaled into the lungs or the nasal mucus membranes, some medications can start to become effective in seconds. Taken orally, times range from roughly 20 to 45 minutes. After 75 minutes you should be experiencing relief.

Can you take Sudafed and Prozac together?

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

It would be easy to say yes, it's OK, and usually it is. However, no one here knows your medical history, so I would not consider those who are sincere in their effort to help you, because they can be sincerely wrong. Always check with your doctor or pharmacists before taking combinations of medication.

Can you take Benadryl with Sudafed?

My dog has allergies and the vet recommended Children's Benadryl tablet formula. You give 1mg per pound of the dog. So a 15 lb dog would get 15mg. However, the tablets for children come as 12.5mg. One tablet seems to work fine for my 15lb dog. Hope this helps!

Is it safe to take phenylephrine with Wellbutrin?

Phenylephrine is in some Hemorrhoidal ointments with a warning to check with your doctor or pharmacist if you are taking depression medications. I take Bupropion (Wellbutrin).

Today I woke from a nap breathing heavily and feeling weak and shaky. May or may not be related, but I will take this issue to my local pharmacist and see what they say.

Can you take Phenylephrine HCI while taking Levaquin?

Yes, I've never seen anything regarding an interaction between the two.

What are the laws for purchusing pseudoephedrine in WY?

As of July 31, 2013, there is a limit to how much pseudoephedrine can be purchased in Indiana. A person can only buy up to 3.6 grams per day, 7.2 grams per month or 61.2 grams per year. Anyone who has been convicted of the illegal manufacturing and use of methamphetamine cannot buy it without a prescription.

Does sudafed have codeine in it?

Exedrine does have caffeine in it, it allows the medicine to work faster and better. Each pill contains 65 milligrams of caffeine. Which is just a tad less than what is in a can of redbull. I am not saying that Excedrine is a bad thing because of it, i personally love it for my migranes but be careful if you are sensitve to caffeine for it may trigger a Migraine attack.

Can you mix Sudafed with excedrin pm?

I take a .25mg xanax to calm me down and 2 excedrin pm's to put me to sleep at night. works like a charm.

Can you take Sudafed with Adderall 25mg?

This is a question that you should ask your pharmacist or physician.

The pharmacist says it depends - if you are legally prescribed Adderall and have a cold or runny nose, go ahead - just follow the directions and do not take more of either drug than it says to.

If you are trying to get high, you have no idea what effect taking drugs will have - people who are legally prescribed drugs have been examined by a doctor, who takes their medical history to be sure it's safe for them to take - and even then, you get side effects, sometimes very serious ones! Taking drugs illegally is just dumb.

Can you take Sudafed and amoxicillin?

Yes, you can take an antiobiotic and a decongestant together. Remember that the antibiotic needs to be taken on a full stomach because it is hard on your digestive system. Remember to take all of the amoxicillin even after you start to feel better. YOu want to kill every bacteria and not leave any hiding out in your body!

Can you mix phenylephrine and pseudoephedrine?

Both are Nasal Decongestants It is NOT advisable to take them together. Most people would be taking these medications for 'cold-like' symptoms. In which plenty of sleep is recommended. When these two medications are taken at the same time they can also cause insomnia and anxiety. Combined they can also cause an increase in your pulse as well as your blood pressure.

Can you take Sudafed with tramadol?

Yes. Sudafed doesnt have any affect on any of those medications

Will pseudoephedrine show up on a drug test?

If you are tested for it they'll find it, but you can just say you had the flu and had to take it. Until the 2005 US law to combat meth production, it was a common decongestant in over-the-counter cold medications.

It was once listed on the International Olympic Committee's anti-doping list.

Can you take Sudafed pe promethazine together?

Probably not. Promethazine is an ingredient in some cough syrups already, and has a similar effect to other ingredients commonly found in cough syrups. If you really feel strongly that you need both, you should ask your pharmacist to recommend one where there won't be an adverse drug interaction.

Phenylephrine HC with levothyroxine?

Phenylephrine HC is a decongestant used to treat nasal and sinus congestion and levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism. Both medications can be used to treat different conditions but should not be taken together due to potential drug interactions.

Possible adverse reactions from combining phenylephrine HC and levothyroxine include:

  • Increased blood pressure
  • Increased heart rate
  • Dizziness
  • Headache
  • Nausea

To avoid these potential drug interactions it is important to talk to your doctor or pharmacist before taking any medications. They can help you decide which medications are safe to take together and which you should avoid.