Advantage: a fuse is guaranteed to pop only when too many amps are pulled, unlike a circuit breaker that may be "accidentally" turned off by some practical joker.
Disadvantage: You must have spares on hand (or go buy them when needed) unlike a circuit breaker which can be reset over and over.
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On the advantage side, fuses are simple, easy, no maintenance required and low cost if compared to circuit breakers. They will clear a fault quicker than a breaker, trip curve not affected by ambient air temperature. On the disavantage side, fuses may cause single phasing and motor failure and they need replacement after every fault clearing.