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The Great Lakes-St. Lawrence region is unique due to its combination of vast freshwater resources, diverse ecosystems, and significant historical and economic importance. It contains the largest group of freshwater lakes in the world by total area, which supports a rich biodiversity and provides essential resources for millions of people. The St. Lawrence River serves as a crucial shipping route, linking the Great Lakes to the Atlantic Ocean, facilitating trade and transportation. Additionally, the area's cultural heritage reflects a blend of Indigenous, French, and English influences, enriching its historical and social landscape.

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