Ohio?
Some southern US cities that start with the letter O:Oak Ridge, TennesseeOcilla, GeorgiaOdessa, TexasOpelika, AlabamaOlive Branch, MississippiOpelousas, LouisianaOrangeburg, South CarolinaOrlando, FloridaOzark, Arkansas
OregonOxford
I am not aware of any cities in Massachusetts that start with the letter O. However, Oxford, Orange, Orleans, Oak Bluff, and Otis are towns in Massachusetts.
orange, orwell, and Orleans
Ocala
Oxford
ittowamba
The Dalles, Oregon
Urbana, IL
Xenia in Ohio.
denver