Yes, you can take the Pennsylvania Turnpike (I-76) from Harrisburg to Bethlehem. However, you'll need to exit the turnpike at the Quakertown interchange (Exit 44) and then take local roads to reach Bethlehem. The route is straightforward and well-marked, making it a convenient option for travelers.
85 miles taking this route:Take PA-100 SOUTH, from Pottstown, to I-76 PENNSYLVANIA TURNPIKE (toll road); follow signs to I-76 WEST to HARRISBURG (EXITS 298-2).Take the PENNSYLVANIA TURNPIKE - WEST, on I-76, to Harrisburg.
Take I-78 WEST (or U.S. 22 WEST to I-78 WEST) to I-81 SOUTH to HARRISBURG.Take I-81 SOUTH to Harrisburg.
Take I-76 WEST to I-83 to HARRISBURG and YORK-BALTIMORE and HARRISBURG at EXIT 242 off I-76 Pennsylvania Turnpike (toll road). This is the WEST HARRISBURG INTERCHANGE.Take I-83 SOUTH to YORK-BALTIMORE to York.
Harrisburg, PA is approximately 243 miles from Pittsburgh, PA. If you travel by car, the best route to take is the PA Turnpike, which is a toll road. Plan to spend about 4 hours driving. In Pennsylvania we generally describe distances with time, for example: from Harrisburg, Pittsburgh is 4 hours away. If you travel by train, the Amtrak Pennsylvanian will take 5.5 hours and costs about $70.00 one way.
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100 miles taking this route:Take the PENNSYLVANIA TURNPIKE (I-76 or I-276) WEST from Philadelphia to PA-283 at EXIT 247 (EAST HARRISBURG exit).Follow signs to PA-283 off the exit ramp; take PA-283 to Elizabethtown.
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A flight from Harrisburg, Pennsylvania to Charlotte, North Carolina would take about an hour and a half. There is about 410 miles between the two locations.
107 miles taking this route:Take PA-100 SOUTH from Pottstown to I-76 PENNSYLVANIA TURNPIKE (toll road) in West Chester.Once you are past the toll booth, follow signs to I-76 WEST to HARRISBURG. Take I-76 WEST to I-83 to YORK-BALITMORE and HARRISBURG at EXIT 242 (HARRISBURG WEST exit). Follow signs past the toll booth to I-83 SOUTH to YORK and BALTIMORE.Take I-83 SOUTH to Baltimore.
288 miles taking this route: <br /><ol><li>Take PA-309 NORTH to I-78 WEST to HARRISBURG.</li><li>Take I-78 WEST to I-81 SOUTH to HARRISBURG.</li><li>Take I-81 SOUTH TO I-76 PENNSYLVAINA TURNPIKE (toll road) at EXIT 52.</li><li>Turn right off the exit ramp and follow signs to I-76 PENNSYLVANIA TURNPIKE (toll road) to PHILADELPHIA and PITTSBURGH.</li><li>Once you are past the toll booth, follow signs to I-76 WEST to PITTSBURGH (for EXITS 201-2). Take I-76 PENNSYLVANIA TURNPIKE (toll road) WEST to Pittsburgh. To access downtown, take I-376 WEST (EXIT 57).</li></ol>
197 miles taking this route:Take PA-982 SOUTH, from Latrobe, to PA-31 EAST to DONEGAL.Take PA-31 EAST to the PENNSYLVANIA TURNPIKE (I-76); follow signs to I-76 EAST to HARRISBURG (to EXITS 110-359).Take I-76 PENNSYLVANIA TURNPIKE (toll) - EAST to I-83 SOUTH to YORK off EXIT 242 (the HARRISBURG WEST interchange).Take I-83 SOUTH to U.S. 30 WEST to GETTYSBURG off EXIT 22 in York.Take U.S. 30 WEST across to the EXIT for PA-74 CARLISLE AVE; take the exit, and then turn left off the exit ramp onto PA-74 CARLISLE AVE - SOUTH.Take PA-74 CARLISLE AVE - SOUTH to York Fairgrounds.
2,158miles