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The Columbian Exchange significantly impacted the United States by introducing a wide variety of new crops and livestock, which transformed agriculture and diets. Crops like potatoes, tomatoes, and maize became staples, enhancing food security and nutrition. Additionally, the exchange facilitated cultural interactions and economic exchanges between Europe and the Americas, laying the groundwork for future trade relationships. However, it also brought diseases that devastated Indigenous populations, altering the demographic landscape of what would become the United States.

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