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The literal answer to your question is Madagascar, a very large island off the coast of Africa which is about 3500 miles south (and 1100 miles to the east) of Greece. It is the largest island located south of Greece. I suspect, however, that what you are asking for the name of the largest of the Greek islands to the south of mainland Greece: that large island in the very south of Greece is Crete.

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16y ago

What else can I help you with?